Non‐small cell lung cancer in China

P Chen, Y Liu, Y Wen, C Zhou - Cancer Communications, 2022 - Wiley Online Library
In China, lung cancer is a primary cancer type with high incidence and mortality. Risk factors
for lung cancer include tobacco use, family history, radiation exposure, and the presence of …

B vitamins and one-carbon metabolism: implications in human health and disease

P Lyon, V Strippoli, B Fang, L Cimmino - Nutrients, 2020 - mdpi.com
Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …

B vitamins and their role in immune regulation and cancer

CT Peterson, DA Rodionov, AL Osterman, SN Peterson - Nutrients, 2020 - mdpi.com
B group vitamins represent essential micronutrients for myriad metabolic and regulatory
processes required for human health, serving as cofactors used by hundreds of enzymes …

Vitamin B12 status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls

A Sobczyńska-Malefora, E Delvin… - Critical reviews in …, 2021 - Taylor & Francis
Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment: JACC Focus Seminar

DJA Jenkins, JD Spence, EL Giovannucci, Y Kim… - Journal of the American …, 2021 - jacc.org
This is an update of the previous 2018 systematic review and meta-analysis of vitamin and
mineral supplementation on cardiovascular disease outcomes and all-cause mortality. New …

Relationship between serum B12 concentrations and mortality: experience in NHANES

BHR Wolffenbuttel, MR Heiner-Fokkema, R Green… - BMC medicine, 2020 - Springer
Background There is conflicting evidence in the literature on the association between
(elevated) serum B12 concentrations and subsequent disease or mortality. We evaluated in …

Effects of vitamin B12 supplementation on cognitive function, depressive symptoms, and fatigue: a systematic review, meta-analysis, and meta-regression

S Markun, I Gravestock, L Jäger, T Rosemann… - Nutrients, 2021 - mdpi.com
Vitamin B12 is often used to improve cognitive function, depressive symptoms, and fatigue.
In most cases, such complaints are not associated with overt vitamin B12 deficiency or …

Systematic review of Mendelian randomization studies on risk of cancer

G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Vitamin B12—Multifaceted in vivo functions and in vitro applications

K Halczuk, J Kaźmierczak-Barańska, BT Karwowski… - Nutrients, 2023 - mdpi.com
Vitamin B12 plays a key role in DNA stability. Research indicates that vitamin B12 deficiency
leads to indirect DNA damage, and vitamin B12 supplementation may reverse this effect …

Lung microbiome alterations in NSCLC patients

L Zheng, R Sun, Y Zhu, Z Li, X She, X Jian, F Yu… - Scientific reports, 2021 - nature.com
Lung is colonized by a diverse array of microbes and the lung microbiota is profoundly
involved in the development of respiratory diseases. There is little knowledge about the role …