Abstract Treatment guidelines developed by the Sinus and Allergy Health Partnership for
acute bacterial rhinosinusitis (ABRS) were originally published in 2000. These guidelines …

Otitis media is the most frequent condition for which children make office visits to physicians;
in 1990, approximately 24.5 million such visits were reported. By 3 years of age …

ContextConcern has been raised about the possible emergence of a bacterial strain that is
untreatable by US Food and Drug Administration (FDA)–approved antibiotics and that …

Reduction of drug-resistant Streptococcus pneumoniae (DRSP) by pneumococcal conjugate
vaccines (PCVs) has recently become a reality. We now know that (1) most clinically …

The capsule is a major virulence factor of pneumococci, and it was shown that some
capsular variants are associated with antimicrobial resistance and certain types of disease …

Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, otitis
media, and sinusitis; it results in significant morbidity and mortality in patients with …

Background. Streptococcus pneumoniae is a major cause of acute otitis media (AOM) in
young children. More than 90 immunologically distinct pneumococcal serotypes have been …

Pneumococcal conjugate vaccines are highly effective in preventing invasive disease in
infants and young children, with favorable safety and immunogenicity profiles. These …

Background: Seven valent pneumococcal conjugate vaccine (PCV7) was licensed and
introduced in 2000 for universal administration of children younger than 2 years of age and …

Background. In the developed societies, day-care centers (DCCs) play an important role in
the spread of antibiotic-resistant pneumococci both within the facility and from the facility to …