[HTML][HTML] Exploring the Multifaceted Potential of Sildenafil in Medicine

C Pușcașu, A Zanfirescu, S Negreș, OC Șeremet - Medicina, 2023 - mdpi.com
Phosphodiesterase type 5 (PDE5) is pivotal in cellular signalling, regulating cyclic
guanosine monophosphate (cGMP) levels crucial for smooth muscle relaxation and …

[PDF][PDF] EVALUATING THE SYNERGISM BETWEEN SILDENAFIL AND METFORMIN IN AN ANIMAL MODEL OF DIABETIC NEUROPATHY INDUCED BY ALLOXAN.

C PUȘCAȘU, A VĂLEANU, E ȘTEFĂNESCU… - …, 2023 - farmaciajournal.com
Given the complex mechanism of diabetic neuropathy, evaluating the effect of drug
combinations in this pathology is of an utmost importance. The aim of this study was to …

[HTML][HTML] The Influence of Sildenafil–Metformin Combination on Hyperalgesia and Biochemical Markers in Diabetic Neuropathy in Mice

C Pușcașu, A Ungurianu, OC Șeremet, C Andrei… - Medicina, 2023 - mdpi.com
Background and objectives: Worldwide, approximately 500 million people suffer from
diabetes and at least 50% of these people develop neuropathy. Currently, therapeutic …