[HTML][HTML] Azathioprine and risk of skin cancer in organ transplant recipients: systematic review and meta-analysis

Z Jiyad, CM Olsen, MT Burke, NM Isbel… - American Journal of …, 2016 - Elsevier
Azathioprine, a purine antimetabolite immunosuppressant, photosensitizes the skin and
causes the production of mutagenic reactive oxygen species. It is postulated to increase the …

Squamous-cell carcinoma of the skin

A Wysong - New England Journal of Medicine, 2023 - Mass Medical Soc
Squamous-Cell Carcinoma of the Skin | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Review of high‐risk features of cutaneous squamous cell carcinoma and discrepancies between the American Joint Committee on Cancer and NCCN Clinical …

SL Skulsky, B O'Sullivan, O McArdle, M Leader… - Head & …, 2017 - Wiley Online Library
Cutaneous squamous cell carcinoma (SCC) is a malignancy that arises from epidermal
keratinocytes. Although the majority of cutaneous SCC cases are easily treated without …

Epidemiology of keratinocyte carcinomas after organ transplantation

MM Madeleine, NS Patel, EI Plasmeijer… - British Journal of …, 2017 - academic.oup.com
Keratinocyte carcinoma (KC) is the most common type of cancer among white populations,
but it is even more common among solid organ transplant recipients (OTRs). The most …

The relationships between cancer and autoimmune rheumatic diseases

LC Cappelli, AA Shah - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Links between autoimmune rheumatic diseases and cancer continue to be elucidated. In
this review, we explore this complex, bidirectional relationship. First, the increased risk of …

Transplant genetics and genomics

JYC Yang, MM Sarwal - Nature Reviews Genetics, 2017 - nature.com
Ever since the discovery of the major histocompatibility complex, scientific and clinical
understanding in the field of transplantation has been advanced through genetic and …

[HTML][HTML] Immunosuppressive drugs

Y Hussain, H Khan - Encyclopedia of infection and immunity, 2022 - ncbi.nlm.nih.gov
Immunosuppressant is a class of medicines that inhibit or decrease the intensity of the
immune response in the body. Most of these medications are used to allow the body less …

[HTML][HTML] Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort

CP Stapleton, KA Birdwell, AJ McKnight… - American Journal of …, 2019 - Elsevier
Renal transplant recipients have an increased risk of non-melanoma skin cancer (NMSC)
compared to in the general population. Here, we show polygenic risk scores (PRS) …

Cutaneous squamous cell cancer (cSCC) risk and the human leukocyte antigen (HLA) system

P Yesantharao, W Wang, NM Ioannidis, S Demehri… - Human immunology, 2017 - Elsevier
Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer among
Caucasians in the United States, with rising incidence over the past decade. Treatment for …

Surfing the big data wave: omics data challenges in transplantation

R Ba, E Geffard, V Douillard, F Simon, L Mesnard… - …, 2022 - journals.lww.com
In both research and care, patients, caregivers, and researchers are facing a leap forward in
the quantity of data that are available for analysis and interpretation, marking the daunting …