Reactive oxygen species, including singlet oxygen, play an important role in the onset and
progression of disease, as well as in aging. Singlet oxygen can be formed non …

Extracellular vesicles (EVs), encompassing exosomes, microvesicles (MVs), and apoptotic
bodies (ABs), are cell-derived heterogeneous nanoparticles with a pivotal role in …

Background Pathological cardiac hypertrophy occurs in response to numerous stimuli and
precedes heart failure (HF). Therapies that ameliorate pathological cardiac hypertrophy are …

Obesity is the main risk factor for many non-communicable diseases. In clinical practice,
unspecific markers are used for the determination of metabolic alterations and inflammation …

Exosomal microRNAs (EXO-miRNAs) are promising non-invasive diagnostic biomarkers for
cardiovascular disease. Heart failure with preserved ejection fraction (HFpEF) is a poorly …

Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

Coronary microvascular endothelial cells (CMECs) react to changes in coronary blood flow
and myocardial metabolites and regulate coronary blood flow by balancing vasoconstrictors …

Background Pulmonary fibrosis is an emerging complication of SARS-CoV-2 infection. In
this study, we speculate that patients with COVID-19 and idiopathic pulmonary fibrosis (IPF) …

Cardiac microvascular injury can be a fundamental pathological process that causes high
incidence cardiovascular diseases such heart failure, diabetic cardiomyopathy, and …

BACKGROUND: Extracellular vesicles (EVs) contain bioactive cargo including miRNAs and
proteins that are released by cells during cell-cell communication. Endothelial cells (ECs) …