Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are
still a neglected topic by public health authorities even though most deaths from fungal …

The prevalence of fungal infections is growing at an alarming pace and the pathogenesis is
still not clearly understood. Recurrence of these fungal diseases is often due to their …

Recurrent vulvovaginal candidiasis is a debilitating, long-term condition that can severely
affect the quality of life of affected women. No estimates of the global prevalence or lifetime …

We characterized the vaginal ecosystem during common infections of the female genital
tract, as vulvovaginal candidiasis (VVC, n= 18) and Chlamydia trachomatis infection (CT, n …

The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Vaginal eubiosis is characterised by beneficial lactobacillus-dominated microbiota. In
contrast, vaginal dysbiosis (eg bacterial vaginosis, BV), characterised by an overgrowth of …

Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

The fungus Candida albicans is an opportunistic pathogen that can exploit imbalances in
microbiome composition to invade its human host, causing pathologies ranging from vaginal …