International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors

J Hamann, G Aust, D Araç, FB Engel… - Pharmacological …, 2015 - Elsevier
The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

Mechanisms of adhesion G protein–coupled receptor activation

A Vizurraga, R Adhikari, J Yeung, M Yu… - Journal of Biological …, 2020 - ASBMB
Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of
Class B GPCRs that control a wide array of physiological processes and are implicated in …

Review of rodent models of attention deficit hyperactivity disorder

SL Regan, MT Williams, CV Vorhees - Neuroscience & Biobehavioral …, 2022 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder
that affects 8–12% of children and> 4% of adults. Environmental factors are believed to …

Structural basis of teneurin-latrophilin interaction in repulsive guidance of migrating neurons

D Del Toro, MA Carrasquero-Ordaz, A Chu, T Ruff… - Cell, 2020 - cell.com
Teneurins are ancient metazoan cell adhesion receptors that control brain development and
neuronal wiring in higher animals. The extracellular C terminus binds the adhesion GPCR …

[HTML][HTML] FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development

ML O'Sullivan, J de Wit, JN Savas, D Comoletti… - Neuron, 2012 - cell.com
Latrophilins (LPHNs) are a small family of G protein-coupled receptors known to mediate the
massive synaptic exocytosis caused by the black widow spider venom α-latrotoxin, but their …

Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology

T Lala, RA Hall - Physiological Reviews, 2022 - journals.physiology.org
Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …

[HTML][HTML] Brain imaging genetics in ADHD and beyond–Mapping pathways from gene to disorder at different levels of complexity

M Klein, M Onnink, M van Donkelaar, T Wolfers… - Neuroscience & …, 2017 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) is a common and often persistent
neurodevelopmental disorder. Beyond gene-finding, neurobiological parameters, such as …

The ADHD-susceptibility gene lphn3. 1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development

M Lange, W Norton, M Coolen, M Chaminade… - Molecular …, 2012 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder
characterized by inattention, hyperactivity, increased impulsivity and emotion dysregulation …

Structural basis of latrophilin-FLRT-UNC5 interaction in cell adhesion

YC Lu, OV Nazarko, R Sando, GS Salzman, NS Li… - Structure, 2015 - cell.com
Fibronectin leucine-rich repeat transmembrane proteins (FLRTs) are cell-adhesion
molecules with emerging functions in cortical development and synapse formation. Their …

Toward developmental models of psychiatric disorders in zebrafish

WHJ Norton - Frontiers in neural circuits, 2013 - frontiersin.org
Psychiatric disorders are a diverse set of diseases that affect all aspects of mental function
including social interaction, thinking, feeling, and mood. Although psychiatric disorders …