The changing therapeutic landscape of metastatic renal cancer

JC Angulo, O Shapiro - Cancers, 2019 - mdpi.com
The practising clinician treating a patient with metastatic clear cell renal cell carcinoma
(CCRCC) faces a difficult task of choosing the most appropriate therapeutic regimen in a …

[HTML][HTML] The role of immunotherapy in advanced renal cell carcinoma

ER Mondlane, P Abreu-Mendes, D Martins… - International braz j …, 2021 - SciELO Brasil
Cancer has become increasingly common worldwide, being the second leading cause of
death and an important barrier to increasing life expectancy in all countries in the XXI …

Phase II trial of stereotactic ablative radiation for oligoprogressive metastatic kidney cancer

R Hannan, M Christensen, H Hammers… - European urology …, 2022 - Elsevier
Background Patients with metastatic renal cell carcinoma (mRCC) treated with systemic
therapy sometimes progress at limited sites. The best treatment approach for patients with …

[HTML][HTML] Differentially expressed autophagy-related genes are potential prognostic and diagnostic biomarkers in clear-cell renal cell carcinoma

B Wan, B Liu, G Yu, Y Huang, C Lv - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
We examined the role of differentially expressed autophagy-related genes (DEARGs) in
clear cell Renal Cell Carcinoma (ccRCC) using high-throughput RNA-seq data from The …

Development and validation of a prognostic immune-associated gene signature in clear cell renal cell carcinoma

C Shen, J Liu, J Wang, X Zhong, D Dong… - International …, 2020 - Elsevier
Background Recent studies have demonstrated that immune-associated genes (IAGs) play
an important role in the occurrence and progression of clear renal clear cell carcinoma …

Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma

C Shen, Z Chen, Y Zhang, W Xu… - Oncology …, 2022 - spandidos-publications.com
Renal cell carcinoma (RCC) remains one of the most lethal urinary tumors in East Asia
despite great advancements in treatment strategies in recent years. Ribosomal protein S20 …

Identification of pyroptosis-related subtypes and comprehensive analysis of characteristics of the tumor microenvironment infiltration in clear cell renal cell carcinoma

J Zeng, P Zhu, Y Tang, C Zhang, C Ye, S Cheng… - Scientific Reports, 2023 - nature.com
Pyroptosis is a kind of programmed cell death triggered by the inflammasome. Growing
evidence has revealed the crucial utility of pyroptosis in tumors. However, the potential …

Second-Line Treatment of Metastatic Renal Cell Carcinoma in the Era of Predictive Biomarkers

AI Parosanu, C Baston, IM Stanciu, CF Parlog, C Nitipir - Diagnostics, 2023 - mdpi.com
Background: Over the past few years, significant advancements have been achieved in the
front-line treatment of metastatic renal cell carcinomas (mRCCs). However, most patients will …

MTA2 as a potential biomarker and its involvement in metastatic progression of human renal cancer by miR-133b targeting MMP-9

YS Chen, TW Hung, SC Su, CL Lin, SF Yang, CC Lee… - Cancers, 2019 - mdpi.com
Metastasis-associated protein 2 (MTA2) was previously known as a requirement to maintain
malignant potentials in several human cancers. However, the role of MTA2 in the …

Construction and verification of a novel prognostic risk model for kidney renal clear cell carcinoma based on immunity-related genes

Y Liu, D Wu, H Chen, L Yan, Q Xiang, Q Li… - Frontiers in …, 2023 - frontiersin.org
Background: Currently, there are no useful biomarkers or prognostic risk markers for the
diagnosis of kidney renal clear cell carcinoma (KIRC), although recent research has shown …