Carica papaya: comprehensive overview of the nutritional values, phytochemicals and pharmacological activities

OR Alara, NH Abdurahman, JA Alara - Advances in traditional medicine, 2020 - Springer
Carica papaya is a perennial large herbaceous plant known for diverse biological activities.
Different parts of this plant such as seeds, leaves, fruits, peels, roots, and stems have been …

Plant cysteine proteinases: evaluation of the pharmacological activity

CE Salas, MTR Gomes, M Hernandez, MTP Lopes - Phytochemistry, 2008 - Elsevier
Cysteine proteinases are involved in virtually every aspect of plant physiology and
development. They play a role in development, senescence, programmed cell death …

The gastric ulcer protective and healing role of cysteine proteinases from Carica candamarcensis

VJ Mello, MTR Gomes, FO Lemos, JL Delfino… - Phytomedicine, 2008 - Elsevier
Latex from Caricaceae contains proteolytic enzymes localized in the fruit, which are used
ethnopharmacologically to treat digestive disorders. Some of these proteins display …

In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain

R Báez, MTP Lopes, CE Salas, M Hernández - Planta medica, 2007 - thieme-connect.com
Abstract Stem bromelain (EC 3.4. 22.32) is a major cysteine proteinase, isolated from
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …

[PDF][PDF] Nutritional, medicinal and pharmacological properties of papaya (Carica papaya linn.): A review

MC Gunde, ND Amnerkar - J Innov Pharm Biol Sci, 2016 - academia.edu
Papaya (Carica papaya linn) is well known for its exceptional nutritional and medicinal
properties throughout the world. From the times immemorial, the whole Papaya plant …

Plant proteinases and inhibitors: an overview of biological function and pharmacological activity

M TR Gomes, ML Oliva, M TP Lopes… - Current Protein and …, 2011 - ingentaconnect.com
Proteinases play a fundamental metabolic role during the life cycle in the plant kingdom. By
interacting with endogenous or exogenous inhibitors, the proteolytic activity is modulated to …

Trends and prospects of plant proteases in therapeutics

AV Balakireva, NV Kuznetsova… - Current medicinal …, 2019 - ingentaconnect.com
The main function of proteases in any living organism is the cleavage of proteins resulting in
the degradation of damaged, misfolded and potentially harmful proteins and therefore …

Plant proteolytic enzymes: Their role as natural pharmacophores

CE Salas, D Dittz, MJ Torres - Biotechnological applications of plant …, 2018 - Springer
Proteases or proteinases are enzymes that catalyze cleavage of proteins at peptide bonds
generating smaller peptides. Some of them are very specific in their choice of target site …

Wound-healing activity of a proteolytic fraction from Carica candamarcensis on experimentally induced burn

FSL Gomes, CV Spínola, HA Ribeiro, MTP Lopes… - Burns, 2010 - Elsevier
Carica candamarcensis is a species from the Caricaceae family whose immature fruit
contains latex with large amounts of cysteine proteinases. In prior studies, we isolated two of …

A supramolecular complex between proteinases and β-cyclodextrin that preserves enzymatic activity: Physicochemical characterization

AML Denadai, MM Santoro, MTP Lopes, A Chenna… - Biodrugs, 2006 - Springer
Background Cyclodextrins are suitable drug delivery systems because of their ability to
subtly modify the physical, chemical, and biological properties of guest molecules through …