Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding?

R Lücking, MC Aime, B Robbertse, AN Miller… - IMA fungus, 2020 - Springer
True fungi (Fungi) and fungus-like organisms (eg Mycetozoa, Oomycota) constitute the
second largest group of organisms based on global richness estimates, with around 3 …

Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

SR Lockhart, KA Etienne, S Vallabhaneni… - Clinical Infectious …, 2017 - academic.oup.com
Background. Candida auris, a multidrug-resistant yeast that causes invasive infections, was
first described in 2009 in Japan and has since been reported from several countries …

Candida auris: a review of the literature

A Jeffery-Smith, SK Taori, S Schelenz… - Clinical microbiology …, 2018 - Am Soc Microbiol
The emerging pathogen Candida auris has been associated with nosocomial outbreaks on
five continents. Genetic analysis indicates the simultaneous emergence of separate clades …

Antifungal drug resistance: evolution, mechanisms and impact

NM Revie, KR Iyer, N Robbins, LE Cowen - Current opinion in …, 2018 - Elsevier
Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

A Chowdhary, C Sharma, JF Meis - PLOS pathogens, 2017 - journals.plos.org
Candidiasis, which includes both superficial infections and invasive disease, is the most
common cause of fungal infection worldwide. Candida bloodstream infections (BSI) cause …

On the emergence of Candida auris: climate change, azoles, swamps, and birds

A Casadevall, DP Kontoyiannis, V Robert - MBio, 2019 - Am Soc Microbiol
The most enigmatic aspect of the rise of Candida auris as a human pathogen is that it
emerged simultaneously on three continents, with each clade being genetically distinct …

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and …

A Chowdhary, A Prakash, C Sharma… - Journal of …, 2018 - academic.oup.com
Background Candida auris has emerged globally as an MDR nosocomial pathogen in ICU
patients. Objectives We studied the antifungal susceptibility of C. auris isolates (n= 350) from …

Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare …

S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …