[HTML][HTML] Potential of stimuli-responsive in situ gel system for sustained ocular drug delivery: Recent progress and contemporary research
M Pandey, H Choudhury, A binti Abd Aziz… - Polymers, 2021 - mdpi.com
Eyesight is one of the most well-deserved blessings, amid all the five senses in the human
body. It captures the raw signals from the outside world to create detailed visual images …
body. It captures the raw signals from the outside world to create detailed visual images …
An overview of PLGA in-situ forming implants based on solvent exchange technique: effect of formulation components and characterization
TM Ibrahim, NA El-Megrab… - Pharmaceutical …, 2021 - Taylor & Francis
As a result of the low oral bioavailability of several drugs, there is a renewed interest for
parenteral administration to target their absorption directly into the blood bypassing the long …
parenteral administration to target their absorption directly into the blood bypassing the long …
Fenofibrate loaded nanofibers based thermo-responsive gel for ocular delivery: Formulation development, characterization and in vitro toxicity study
This research work is to develop nanofiber loaded in-situ gel for the delivery of fenofibrate to
the posterior ocular site. Fenofibrate had showed its efficacy in neovascular ocular diseases …
the posterior ocular site. Fenofibrate had showed its efficacy in neovascular ocular diseases …
[HTML][HTML] Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: in vitro and in vivo studies
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …
Development, evaluation and recent progress of ocular in situ gelling drug delivery vehicle based on poloxamer 407
M Dewan, A Adhikari, R Jana… - Journal of Drug Delivery …, 2023 - Elsevier
The fabrication of an effective in situ gelling ophthalmic drug delivery vehicle is recently
received enormous interest to overcome the demerits of conventional ocular solutions and …
received enormous interest to overcome the demerits of conventional ocular solutions and …
In vitro–in vivo evaluation of tetrahydrozoline‐loaded ocular in situ gels on rabbits for allergic conjunctivitis management
Ocular allergy is one of the most common disorders of the eye surface. The conventional eye
drops lack of therapeutic efficacy due to low ocular bioavailability and decreased drug …
drops lack of therapeutic efficacy due to low ocular bioavailability and decreased drug …
Lipid complex-itraconazole in thermosensitive mucoadhesive vaginal gel to enhance the effectiveness of therapy for vulvovaginal candidiasis: Formulation …
Purpose This study aimed to produce lipid complex-ITR (CL-ITR) to enhance the solubility of
ITR which is then made into an in situ vaginal gel to maximize the local therapeutic effect of …
ITR which is then made into an in situ vaginal gel to maximize the local therapeutic effect of …
[HTML][HTML] Natural ergot alkaloids in ocular pharmacotherapy: Known molecules for novel nanoparticle-based delivery systems
Several pharmacological properties are attributed to ergot alkaloids as a result of their
antibacterial, antiproliferative, and antioxidant effects. Although known for their biomedical …
antibacterial, antiproliferative, and antioxidant effects. Although known for their biomedical …
Enhanced localization of cefazoline sodium in the ocular tissue using thermosensitive-mucoadhesive hydrogels: Formulation development, hemocompatibility and in …
MA Fiqri, U Athiyyah, P Layadi, TGA Fadjar… - Journal of Drug Delivery …, 2022 - Elsevier
Bacterial keratitis is an eye infectious disease which became a global concern due to its
impact to visual impairment in worldwide. Cefazolin (CFZ) is the first-line drug for the …
impact to visual impairment in worldwide. Cefazolin (CFZ) is the first-line drug for the …
In vitro-in vivo evaluation of olopatadine incorporated chitosan nanoparticles for the treatment of ocular allergy
In this study, antihistaminic agent Olopatadine hydrochloride (OLO) was incorporated into
chitosan nanoparticles for the treatment of ocular allergy. Nanoparticles were prepared with …
chitosan nanoparticles for the treatment of ocular allergy. Nanoparticles were prepared with …