[HTML][HTML] Boron delivery agents for neutron capture therapy of cancer
RF Barth, P Mi, W Yang - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …
Boron in cancer therapeutics: An overview
S Kulkarni, D Bhandary, Y Singh, V Monga… - Pharmacology & …, 2023 - Elsevier
Boron has become crucial weapon in anticancer research due to significant intervention in
the cell proliferation. Being an excellent bio-isosteric replacement for carbon, it has …
the cell proliferation. Being an excellent bio-isosteric replacement for carbon, it has …
[HTML][HTML] Boron neutron capture therapy: Moving toward targeted cancer therapy
Boron neutron capture therapy (BNCT) occurs when a stable isotope, boton-10, is irradiated
with low-energy thermal neutrons to yield stripped down helium-4 nuclei and lithium-7 …
with low-energy thermal neutrons to yield stripped down helium-4 nuclei and lithium-7 …
[HTML][HTML] Evaluation of a Novel Boron-Containing α-d-Mannopyranoside for BNCT
T Tsurubuchi, M Shirakawa, W Kurosawa, K Matsumoto… - Cells, 2020 - mdpi.com
Boron neutron capture therapy (BNCT) is a unique anticancer technology that has
demonstrated its efficacy in numerous phase I/II clinical trials with boronophenylalanine …
demonstrated its efficacy in numerous phase I/II clinical trials with boronophenylalanine …
[HTML][HTML] Design, synthesis, and utility of defined molecular scaffolds
A growing theme in chemistry is the joining of multiple organic molecular building blocks to
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
[HTML][HTML] Dendritic Structures Functionalized with Boron Clusters, in Particular Carboranes, and Their Biological Properties
AM Caminade, M Milewski, E Hey-Hawkins - Pharmaceutics, 2023 - mdpi.com
The presence of a large number of boron atoms in boron clusters make them attractive tools
for the treatment of cancer using boron neutron capture therapy (BNCT). Since the quantity …
for the treatment of cancer using boron neutron capture therapy (BNCT). Since the quantity …
In vivo investigation of boron-rich nanodrugs for treating triple-negative breast cancers via boron neutron capture therapy
KW Lan, WY Huang, YL Chiu, FT Hsu, YC Chien… - Biomaterials …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is characterized by highly proliferative cancer cells
and is the only subtype of breast cancer that lacks a targeted therapy. Boron neutron capture …
and is the only subtype of breast cancer that lacks a targeted therapy. Boron neutron capture …
Boron‐Containing Probes for Non‐optical High‐Resolution Imaging of Biological Samples
S Kabatas, P Agüi‐Gonzalez, KA Saal… - Angewandte …, 2019 - Wiley Online Library
Boron has been employed in materials science as a marker for imaging specific structures
by electron energy loss spectroscopy (EELS) or secondary ion mass spectrometry (SIMS). It …
by electron energy loss spectroscopy (EELS) or secondary ion mass spectrometry (SIMS). It …
Multivalent glycosylated nanoparticles for studying carbohydrate–protein interactions
AK Adak, HJ Lin, CC Lin - Organic & Biomolecular Chemistry, 2014 - pubs.rsc.org
Carbohydrates are essential mediators of many important extracellular binding events.
Multivalent effects are often required for these binding interactions that are generally weak …
Multivalent effects are often required for these binding interactions that are generally weak …
[HTML][HTML] Modular triazine-based carborane-containing carboxylic acids–synthesis and characterisation of potential boron neutron capture therapy agents made of …
Based on a modular combination of s-triazine, the well-known 9-mercapto-1, 7-dicarba-
closo-dodecaborane (12) and commercially available carboxylic acids, namely thioglycolic …
closo-dodecaborane (12) and commercially available carboxylic acids, namely thioglycolic …