Rheumatoid arthritis—common origins, divergent mechanisms

EM Gravallese, GS Firestein - New England Journal of Medicine, 2023 - Mass Medical Soc
Rheumatoid Arthritis — Common Origins, Divergent Mechanisms | NEJM Skip to main content
NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

[HTML][HTML] Autoantibodies in rheumatoid arthritis: historical background and novel findings

MV Sokolova, G Schett, U Steffen - Clinical reviews in allergy & …, 2022 - Springer
Autoantibodies represent a hallmark of rheumatoid arthritis (RA), with the rheumatoid factor
(RF) and antibodies against citrullinated proteins (ACPA) being the most acknowledged …

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara… - Nature …, 2022 - nature.com
Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-
ancestry genetic research of RA promises to improve power to detect genetic signals, fine …

[HTML][HTML] Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis

X Wu, Y Liu, S Jin, M Wang, Y Jiao, B Yang… - Nature …, 2021 - nature.com
The presence or absence of anti-citrullinated peptide antibodies (ACPA) and associated
disparities in patients with rheumatoid arthritis (RA) implies disease heterogeneity with …

Patients with seronegative RA have more inflammatory activity compared with patients with seropositive RA in an inception cohort of DMARD-naïve patients classified …

LB Nordberg, S Lillegraven, E Lie, AB Aga… - Annals of the …, 2017 - ard.bmj.com
Objectives To compare the presentation of seropositive and seronegative early rheumatoid
arthritis (RA) in disease-modifying antirheumatic drug (DMARD)-naïve patients classified …

[HTML][HTML] CCN1 Promotes Inflammation by Inducing IL-6 Production via α6β1/PI3K/Akt/NF-κB Pathway in Autoimmune Hepatitis

R Jiang, J Tang, X Zhang, Y He, Z Yu, S Chen… - Frontiers in …, 2022 - frontiersin.org
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease with unknown etiology.
CCN1, an extracellular matrix-associated protein, is associated with carcinoma …

[HTML][HTML] Epidemiology of rheumatoid arthritis in Korea

H Kim, YK Sung - Journal of Rheumatic Diseases, 2021 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterised by
symmetrical involvement of the joints, associated extra-articular manifestations and …

Integrated nanomaterials for non-invasive photothermal therapy of rheumatoid arthritis

A Gadeval, S Chaudhari, SP Bollampally, S Polaka… - Drug discovery today, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease that
causes swelling, redness, and arthralgia of multiple joints. Despite significant research and …

Cardiovascular risk in patients with rheumatoid arthritis

K Lauper, C Gabay - Seminars in Immunopathology, 2017 - Springer
Substantial epidemiologic data have shown an increased risk of cardiovascular (CV)
disease in rheumatoid arthritis (RA) patients. Traditional CV risk factors may partly contribute …

B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure

F Rivellese, F Humby, S Bugatti… - Arthritis & …, 2020 - Wiley Online Library
Objective To define the relationship of synovial B cells to clinical phenotypes at different
stages of disease evolution and drug exposure in rheumatoid arthritis (RA). Methods …