[HTML][HTML] RNA duplex map in living cells reveals higher-order transcriptome structure
RNA has the intrinsic property to base pair, forming complex structures fundamental to its
diverse functions. Here, we develop PARIS, a method based on reversible psoralen …
diverse functions. Here, we develop PARIS, a method based on reversible psoralen …
Jarid2 methylation via the PRC2 complex regulates H3K27me3 deposition during cell differentiation
S Sanulli, N Justin, A Teissandier, K Ancelin, M Portoso… - Molecular cell, 2015 - cell.com
Summary Polycomb Group (PcG) proteins maintain transcriptional repression throughout
development, mostly by regulating chromatin structure. Polycomb Repressive Complex 2 …
development, mostly by regulating chromatin structure. Polycomb Repressive Complex 2 …
Regulatory interactions between RNA and polycomb repressive complex 2
C Cifuentes-Rojas, AJ Hernandez, K Sarma, JT Lee - Molecular cell, 2014 - cell.com
Summary Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that is
localized to thousands of mammalian genes. Though important to human disease and as a …
localized to thousands of mammalian genes. Though important to human disease and as a …
[HTML][HTML] Jarid2 is implicated in the initial Xist-induced targeting of PRC2 to the inactive X chromosome
ST da Rocha, V Boeva, M Escamilla-Del-Arenal… - Molecular cell, 2014 - cell.com
During X chromosome inactivation (XCI), the Polycomb Repressive Complex 2 (PRC2) is
thought to participate in the early maintenance of the inactive state. Although Xist RNA is …
thought to participate in the early maintenance of the inactive state. Although Xist RNA is …
Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA
C Davidovich, X Wang, C Cifuentes-Rojas… - Molecular cell, 2015 - cell.com
Summary Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required
for epigenetic silencing during development and cancer. Early works suggested binding …
for epigenetic silencing during development and cancer. Early works suggested binding …
ATRX directs binding of PRC2 to Xist RNA and Polycomb targets
X chromosome inactivation (XCI) depends on the long noncoding RNA Xist and its
recruitment of Polycomb Repressive Complex 2 (PRC2). PRC2 is also targeted to other sites …
recruitment of Polycomb Repressive Complex 2 (PRC2). PRC2 is also targeted to other sites …
[HTML][HTML] CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis
We reported that Cullin4B-Ring E3 ligase complex (CRL4B) is physically associated with
Polycomb-repressive complex 2 (PRC2). We showed that CRL4B possesses an intrinsic …
Polycomb-repressive complex 2 (PRC2). We showed that CRL4B possesses an intrinsic …
ATP-dependent roX RNA remodeling by the helicase maleless enables specific association of MSL proteins
Dosage compensation in Drosophila involves a global activation of genes on the male X
chromosome. The activating complex (MSL-DCC) consists of male-specific-lethal (MSL) …
chromosome. The activating complex (MSL-DCC) consists of male-specific-lethal (MSL) …
[PDF][PDF] Secondary structural analysis of human lncRNAs
Y Lin - 2018 - kilthub.cmu.edu
In the past decade, long noncoding RNAs (lncRNAs) have been increasingly recognized as
important regulators of gene expression at various levels (1). The human genome encodes …
important regulators of gene expression at various levels (1). The human genome encodes …