Abstract l-asparaginase is a critical part of the treatment of acute lymphoblastic leukaemia in
children and adolescents, and has contributed to the improvement in patient outcomes over …

L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …

Background L-asparaginase is a potential therapeutic enzyme widely used in the
chemotherapy protocols of pediatric and adult patients with acute lymphoblastic leukemia …

Abstract L-asparaginase (LA), an enzyme with anticancer activities, produced by marine-
derived Aspergillus niger was subjected to purification and characterization. The purified …

Abstract L-asparaginase (L-ASNase) from microbial sources is a commercially vital enzyme
to treat acute lymphoblastic leukemia. However, the side effects associated with the …

L-asparaginase (ASNase) enzyme has limited therapeutic use due to its poor
pharmacokinetics and immunogenicity. To overcome these obstacles, we immobilized …

L-asparaginase is an enzyme used as a biopharmaceutical to treat acute lymphoblastic
leukemia. Several adverse effects have been related to L-asparaginase use, so the scientific …

Background Colorectal cancer which is related to genetic and environmental risk factors, is
among the most prevalent life-threatening cancers. Although several pathogenic bacteria …

Purpose Combination therapy is increasingly used as a primary cancer treatment regimen.
In this report, we designed EGFR peptide decorated nanoparticles (NPs) to co-deliver …

The exploration of new sources of L-asparaginase with low glutaminase activity is of great
interest in both medical and food applications. In the current study, a novel L-asparaginase …