Use of baculovirus expression system for generation of virus-like particles: successes and challenges
F Liu, X Wu, L Li, Z Liu, Z Wang - Protein expression and purification, 2013 - Elsevier
The baculovirus expression system (BES) has been one of the versatile platforms for the
production of recombinant proteins requiring multiple post-translational modifications, such …
production of recombinant proteins requiring multiple post-translational modifications, such …
Insect cell technology is a versatile and robust vaccine manufacturing platform
Baculovirus and insect cell culture technologies have mostly been limited to research
laboratories for the transient expression of target proteins for drug development purposes …
laboratories for the transient expression of target proteins for drug development purposes …
Co-expression vs. co-infection using baculovirus expression vectors in insect cell culture: Benefits and drawbacks
The baculovirus expression vector system (BEVS) is a versatile and powerful platform for
protein expression in insect cells. With the ability to approach similar post-translational …
protein expression in insect cells. With the ability to approach similar post-translational …
Challenges for the production of virus-like particles in insect cells: the case of rotavirus-like particles
LA Palomares, OT Ramírez - Biochemical Engineering Journal, 2009 - Elsevier
Virus-like particles (VLP) are formed when viral structural proteins are produced in an
heterologous expression system. Such proteins assemble into structures that are …
heterologous expression system. Such proteins assemble into structures that are …
Production of rabies VLPs in insect cells by two monocistronic baculoviruses approach
TC Bernardino, RM Astray, CA Pereira… - Molecular …, 2021 - Springer
Rabies is an ancient zoonotic disease that still causes the death of over 59,000 people
worldwide each year. The rabies lyssavirus encodes five proteins, including the envelope …
worldwide each year. The rabies lyssavirus encodes five proteins, including the envelope …
Modeling rotavirus-like particles production in a baculovirus expression vector system: Infection kinetics, baculovirus DNA replication, mRNA synthesis and protein …
A Roldão, HLA Vieira, A Charpilienne, D Poncet… - Journal of …, 2007 - Elsevier
Rotavirus is the most common cause of severe diarrhoea in children worldwide, responsible
for more than half a million deaths in children per year. Rotavirus-like particles (Rota VLPs) …
for more than half a million deaths in children per year. Rotavirus-like particles (Rota VLPs) …
[HTML][HTML] Utility of alternative promoters for foreign gene expression using the baculovirus expression vector system
The baculovirus expression vector system (BEVS) is a widely used platform for recombinant
protein production for use in a wide variety of applications. Of particular interest is production …
protein production for use in a wide variety of applications. Of particular interest is production …
Immunogenicity and virus-like particle formation of rotavirus capsid proteins produced in transgenic plants
YM Yang, X Li, H Yang, Y Qian, Y Zhang… - Science china life …, 2011 - Springer
The human pathogen, group A rotavirus, is the most prevalent cause of acute infantile and
pediatric gastroenteritis worldwide, especially in developing countries. There is an urgent …
pediatric gastroenteritis worldwide, especially in developing countries. There is an urgent …
[HTML][HTML] Population kinetics during simultaneous infection of insect cells with two different recombinant baculoviruses for the production of rotavirus-like particles
Background The simultaneous production of various recombinant proteins in every cell of a
culture is often needed for the production of virus-like particles (VLP) or vectors for gene …
culture is often needed for the production of virus-like particles (VLP) or vectors for gene …
Baculovirus-derived vectors for immunization and therapeutic applications
Baculoviruses are arthropod-specific, enveloped viruses with circular, supercoiled double-
stranded deoxyribonucleic acid genomes. While many viruses are studied to seek solutions …
stranded deoxyribonucleic acid genomes. While many viruses are studied to seek solutions …