Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …

The recent outbreak of the COVID-19 pandemic in 2020 reasserted the necessity of artificial
lung membrane technology to treat patients with acute lung failure. In addition, the aging …

Three-dimensional models of kidney tissue that recapitulate human responses are needed
for drug screening, disease modeling, and, ultimately, kidney organ engineering. Here, we …

The bioartificial kidney (BAK) aims at improving dialysis by developing 'living membranes'
for cells-aided removal of uremic metabolites. Here, unique human conditionally …

End stage renal disease (ESRD, or kidney failure) affects∼ 10% of the world's population.
Kidney transplantation, which best duplicates native kidney function, can extend the …

Introduction: Since the advent of peritoneal dialysis (PD) in the 1970s, the principles of
dialysis have changed little. In the coming decades, several major breakthroughs are …

For patients with severe kidney or liver failure the best solution is currently organ
transplantation. However, not all patients are eligible for transplantation and due to limited …

Hollow fiber bioreactors are the focus of scientific research aiming to mimic physiological
vascular networks and engineer organs and tissues in vitro. The reason for this lies in the …

The limited removal of metabolic waste products in dialyzed kidney patients leads to high
morbidity and mortality. One powerful solution for a more complete removal of those …

Patients with end-stage kidney disease (ESKD) suffer from high levels of protein-bound
uremic toxins (PBUTs) that contribute to various comorbidities. Conventional dialysis …