The pig as an animal model for human pathologies: A proteomics perspective

A Bassols, C Costa, PD Eckersall… - PROTEOMICS …, 2014 - Wiley Online Library
Traditional biomedical models are easy to manage in experimental facilities and allow fast
and affordable basic genetic studies related to human disorders, but in some cases they do …

[HTML][HTML] TNF receptors: signaling pathways and contribution to renal dysfunction

RS Al-Lamki, TN Mayadas - Kidney international, 2015 - Elsevier
Tumor necrosis factor (TNF), initially reported to induce tumor cell apoptosis and cachexia, is
now considered a central mediator of a broad range of biological activities from cell …

Tumor necrosis factor receptor 2: its contribution to acute cellular rejection and clear cell renal carcinoma

J Wang, RS Al-Lamki - BioMed Research International, 2013 - Wiley Online Library
Tumor necrosis factor receptor 2 (TNFR2) is a type I transmembrane glycoprotein and one of
the two receptors that orchestrate the complex biological functions of tumor necrosis factor …

Bioinformatic analysis as a first step to predict the compatibility of hematopoiesis and immune system genes between humans and pigs

J Zhang, Y Xu, Y Zhang, EA Bossila, M Shi… - …, 2022 - Wiley Online Library
The shortage of allogeneic donor organs leaves its supply far short of clinical need. There
are great expectations on xenotransplantation, especially with pigs' organs. With the genetic …

Characterization of putative regulatory isoforms of porcine tumor necrosis factor receptor 2 in endothelial cells

M Uribe‐Herranz, SG Kuguel, K Casós… - …, 2020 - Wiley Online Library
Tumor necrosis factor α (TNFα) and its receptors contribute to rejection of transplanted cells
and organs. To elucidate how TNFα affects xenograft rejection, we previously cloned the …

Cloning and expression analyses of pig genes

M Uribe-Herranz, C Costa - Xenotransplantation: Methods and Protocols, 2012 - Springer
Understanding the molecular bases of xenograft rejection is one of the highest priorities in
the xenotransplantation field. Furthermore, the identification of physiological …

Tools for Molecular Studies in Xenotransplantation

SG Kuguel, M Uribe-Herranz, C Costa - Xenotransplantation: Methods and …, 2020 - Springer
Understanding the molecular bases of xenograft rejection is one of the highest priorities in
the xenotransplantation field. This information is needed for the successful development of …

[引用][C] Xenotransplantation literature update, March–April 2011

MKJ Schneider, JD Seebach - Xenotransplantation, 2011 - Wiley Online Library
Schneider MKJ, Seebach JD. Xenotransplantation literature update, March–April 2011.
Xenotransplantation 2011; 18: 209–213.© 2011 John Wiley & Sons A/S.