Droplet microfluidics for high-throughput analysis of antibiotic susceptibility in bacterial cells and populations
W Postek, P Garstecki - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Antibiotic-resistant bacteria are an increasing concern both in everyday life and
specialized environments such as healthcare. As the rate of antibiotic-resistant infections …
specialized environments such as healthcare. As the rate of antibiotic-resistant infections …
Optimization of the hemolysis assay for the assessment of cytotoxicity
In vitro determination of hemolytic properties is a common and important method for
preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical …
preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical …
Probing antimicrobial resistance and sanitizer tolerance themes and their implications for the food industry through the Listeria monocytogenes lens
R Bland, SRB Brown, J Waite‐Cusic… - … Reviews in Food …, 2022 - Wiley Online Library
The development of antibiotic resistance is a serious public health crisis, reducing our ability
to effectively combat infectious bacterial diseases. The parallel study of reduced …
to effectively combat infectious bacterial diseases. The parallel study of reduced …
[HTML][HTML] Specifically targeted antimicrobial peptides synergize with bacterial-entrapping peptide against systemic MRSA infections
Introduction The design of precision antimicrobials aims to personalize the treatment of drug-
resistant bacterial infections and avoid host microbiota dysbiosis. Objectives This study …
resistant bacterial infections and avoid host microbiota dysbiosis. Objectives This study …
Artificial intelligence-driven antimicrobial peptide discovery
P Szymczak, E Szczurek - Current Opinion in Structural Biology, 2023 - Elsevier
Antimicrobial peptides (AMPs) emerge as promising agents against antimicrobial resistance,
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
Revealing the mechanisms of synergistic action of two magainin antimicrobial peptides
B Bechinger, DW Juhl, E Glattard… - Frontiers in Medical …, 2020 - frontiersin.org
The study of peptide-lipid and peptide-peptide interactions as well as their topology and
dynamics using biophysical and structural approaches have changed our view how …
dynamics using biophysical and structural approaches have changed our view how …
Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infection
Chronic wounds frequently become infected with bacterial biofilms which respond poorly to
antibiotic therapy. Aminoglycoside antibiotics are ineffective at treating deep-seated wound …
antibiotic therapy. Aminoglycoside antibiotics are ineffective at treating deep-seated wound …
How to combat gram-negative bacteria using antimicrobial peptides: a challenge or an unattainable goal?
A Barreto-Santamaría, G Arévalo-Pinzón, MA Patarroyo… - Antibiotics, 2021 - mdpi.com
Antimicrobial peptides (AMPs) represent a promising and effective alternative for combating
pathogens, having some advantages compared to conventional antibiotics. However, AMPs …
pathogens, having some advantages compared to conventional antibiotics. However, AMPs …
Lung antimicrobial proteins and peptides: From host defense to therapeutic strategies
YP Di, JM Kuhn, ML Mangoni - Physiological Reviews, 2024 - journals.physiology.org
Representing severe morbidity and mortality globally, respiratory infections associated with
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …
Perturbation-specific transcriptional mapping for unbiased target elucidation of antibiotics
KP Romano, J Bagnall, T Warrier, J Sullivan… - Proceedings of the …, 2024 - pnas.org
The rising prevalence of antibiotic resistance threatens human health. While more
sophisticated strategies for antibiotic discovery are being developed, target elucidation of …
sophisticated strategies for antibiotic discovery are being developed, target elucidation of …