[HTML][HTML] The SH-SY5Y cell line in Parkinson's disease research: a systematic review
H Xicoy, B Wieringa, GJM Martens - Molecular neurodegeneration, 2017 - Springer
Parkinson's disease (PD) is a devastating and highly prevalent neurodegenerative disease
for which only symptomatic treatment is available. In order to develop a truly effective …
for which only symptomatic treatment is available. In order to develop a truly effective …
Advancement in the modelling and therapeutics of Parkinson's disease
SN Rai, P Singh - Journal of chemical neuroanatomy, 2020 - Elsevier
Since the discovery of L-dopa in the middle of the 20th century (1960s), there is not any
neuroprotective therapy available although significant development has been made in the …
neuroprotective therapy available although significant development has been made in the …
Control of cell state transitions
Understanding cell state transitions and purposefully controlling them is a longstanding
challenge in biology. Here we present cell state transition assessment and regulation …
challenge in biology. Here we present cell state transition assessment and regulation …
[HTML][HTML] Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling …
MA Martínez, JL Rodríguez, B Lopez-Torres… - Environment …, 2020 - Elsevier
Glyphosate-containing herbicides are the most used agrochemicals in the world. Their
indiscriminate application raises some concerns regarding the possible health and …
indiscriminate application raises some concerns regarding the possible health and …
Characterization of differentiated SH-SY5Y as neuronal screening model reveals increased oxidative vulnerability
JI Forster, S Köglsberger, C Trefois… - Journal of …, 2016 - journals.sagepub.com
The immortalized and proliferative cell line SH-SY5Y is one of the most commonly used cell
lines in neuroscience and neuroblastoma research. However, undifferentiated SH-SY5Y …
lines in neuroscience and neuroblastoma research. However, undifferentiated SH-SY5Y …
[HTML][HTML] The cellular model for Alzheimer's disease research: PC12 cells
D Xie, T Deng, Z Zhai, T Sun, Y Xu - Frontiers in Molecular …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive decline and irreversible memory impairment …
characterized by progressive cognitive decline and irreversible memory impairment …
[HTML][HTML] RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
SH Choi, MN Flamand, B Liu, H Zhu, M Hu, M Wang… - Cell reports, 2022 - cell.com
Summary N 6-methyladenosine (m 6 A) is deposited co-transcriptionally on thousands of
cellular mRNAs and plays important roles in mRNA processing and cellular function. m 6 A …
cellular mRNAs and plays important roles in mRNA processing and cellular function. m 6 A …
[HTML][HTML] Neuroprotective and anti-inflammatory effects of linoleic acid in models of parkinson's disease: the implication of lipid droplets and lipophagy
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease after
Alzheimer's disease. The principal pathological feature of PD is the progressive loss of …
Alzheimer's disease. The principal pathological feature of PD is the progressive loss of …
[HTML][HTML] Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice
SF Xu, YH Zhang, S Wang, ZQ Pang, YG Fan, JY Li… - Redox biology, 2019 - Elsevier
Brain iron accumulation is common in patients with Parkinson's disease (PD). Iron chelators
have been investigated for their ability to prevent neurodegenerative diseases with features …
have been investigated for their ability to prevent neurodegenerative diseases with features …
[HTML][HTML] Neuroprotective effect of luteolin-7-O-glucoside against 6-OHDA-induced damage in undifferentiated and RA-differentiated SH-SY5Y cells
SCH Rehfeldt, J Silva, C Alves, S Pinteus… - International Journal of …, 2022 - mdpi.com
Luteolin is one of the most common flavonoids present in edible plants and its potential
benefits to the central nervous system include decrease of microglia activation, neuronal …
benefits to the central nervous system include decrease of microglia activation, neuronal …