New developments in liposomal drug delivery

BS Pattni, VV Chupin, VP Torchilin - Chemical reviews, 2015 - ACS Publications
New Developments in Liposomal Drug Delivery | Chemical Reviews ACS ACS Publications
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Lyophilization of liposomal formulations: still necessary, still challenging

S Franzé, F Selmin, E Samaritani, P Minghetti… - Pharmaceutics, 2018 - mdpi.com
Nowadays, the freeze-drying of liposome dispersions is still necessary to provide a solid
dosage form intended for different routes of administration (ie, parenteral, oral, nasal and/or …

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

JJ Moon, H Suh, A Bershteyn, MT Stephan, H Liu… - Nature materials, 2011 - nature.com
Vaccines based on recombinant proteins avoid the toxicity and antivector immunity
associated with live vaccine (for example, viral) vectors, but their immunogenicity is poor …

Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses

MO Oyewumi, A Kumar, Z Cui - Expert review of vaccines, 2010 - Taylor & Francis
The development of novel immune adjuvants is emerging as a significant area of vaccine
delivery based on the continued necessity to amplify immune responses to a wide array of …

An overview of liposome lyophilization and its future potential

C Chen, D Han, C Cai, X Tang - Journal of controlled release, 2010 - Elsevier
Lyophilization is a promising approach to ensure the long-term stability of liposomes. After
decades of studies in this field, different lyoprotective mechanisms, such as water …

Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens

Y Perrie, AR Mohammed, DJ Kirby, SE McNeil… - International journal of …, 2008 - Elsevier
Vaccination remains a key tool in the protection and eradication of diseases. However, the
development of new safe and effective vaccines is not easy. Various live organism based …

[HTML][HTML] Liposomes as sterile preparations and limitations of sterilisation techniques in liposomal manufacturing

MR Toh, GNC Chiu - Asian Journal of Pharmaceutical Sciences, 2013 - Elsevier
Liposomes have been widely researched as a delivery system and there have been many
manufacturing techniques used in the production of liposomal preparations, the most …

Stabilization of liposomes during drying

PT Ingvarsson, M Yang, HM Nielsen… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: During the past 40 years, liposomes have been investigated intensively as drug
carriers for anticancer drugs and as the adjuvant components of vaccines, for example. In …

Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce …

M Henriksen-Lacey, D Christensen… - Journal of controlled …, 2010 - Elsevier
With respect to liposomes as delivery vehicles and adjuvants for vaccine antigens, the role
of vesicle surface charge remains disputed. In the present study we investigate the influence …

Liposomal vaccine delivery systems

M Henriksen-Lacey, KS Korsholm… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Liposomes remain at the forefront of drug and vaccine design owing to their
well-documented abilities to act as delivery vehicles. Nevertheless, the concept of liposomes …