Epigenetics of stress, addiction, and resilience: therapeutic implications
JL Cadet - Molecular neurobiology, 2016 - Springer
Substance use disorders (SUDs) are highly prevalent. SUDs involve vicious cycles of binges
followed by occasional periods of abstinence with recurrent relapses despite treatment and …
followed by occasional periods of abstinence with recurrent relapses despite treatment and …
Drugs and addiction: an introduction to epigenetics
Addiction is a debilitating psychiatric disorder, with a complex aetiology involving the
interaction of inherited predispositions and environmental factors. Emerging evidence …
interaction of inherited predispositions and environmental factors. Emerging evidence …
Sex and estrous cycle effects on anxiety-and depression-related phenotypes in a two-hit developmental stress model
Stress during sensitive developmental periods can adversely affect physical and
psychological development and contribute to later-life mental disorders. In particular …
psychological development and contribute to later-life mental disorders. In particular …
Epigenetic effects induced by methamphetamine and methamphetamine‐dependent oxidative stress
F Limanaqi, S Gambardella, F Biagioni… - Oxidative medicine …, 2018 - Wiley Online Library
Methamphetamine is a widely abused drug, which possesses neurotoxic activity and
powerful addictive effects. Understanding methamphetamine toxicity is key beyond the field …
powerful addictive effects. Understanding methamphetamine toxicity is key beyond the field …
Epigenetic landscape of amphetamine and methamphetamine addiction in rodents
Amphetamine and methamphetamine addiction is described by specific behavioral
alterations, suggesting long-lasting changes in gene and protein expression within specific …
alterations, suggesting long-lasting changes in gene and protein expression within specific …
Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner
Epigenetic mechanisms, such as histone modifications, regulate responsiveness to drugs of
abuse, such as cocaine, but relatively little is known about the regulation of addictive-like …
abuse, such as cocaine, but relatively little is known about the regulation of addictive-like …
DNA methylation and psychiatric disorders
DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …
Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia
M Koga, H Ishiguro, S Yazaki, Y Horiuchi… - Human molecular …, 2009 - academic.oup.com
Chromatin remodeling may play a role in the neurobiology of schizophrenia and the
process, therefore, may be considered as a therapeutic target. The SMARCA2 gene …
process, therefore, may be considered as a therapeutic target. The SMARCA2 gene …
CDKL5 is a brain MeCP2 target gene regulated by DNA methylation
Rett syndrome and its “early-onset seizure” variant are severe neurodevelopmental
disorders associated with mutations within the MECP2 and the CDKL5 genes …
disorders associated with mutations within the MECP2 and the CDKL5 genes …
[PDF][PDF] Why schizophrenia genetics needs epigenetics: a review
N Maric, D Svrakic - Psychiatria Danubina, 2012 - hrcak.srce.hr
WHY SCHIZOPHRENIA GENETICS NEEDS EPIGENETICS: A REVIEW Page 1 2
Psychiatria Danubina, 2012; Vol. 24, No. 1, pp 2–18 Review © Medicinska naklada - Zagreb …
Psychiatria Danubina, 2012; Vol. 24, No. 1, pp 2–18 Review © Medicinska naklada - Zagreb …