Metastasis remains the greatest challenge in the clinical management of cancer. Cell motility
is a fundamental and ancient cellular behaviour that contributes to metastasis and is …

Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

Directional cell migration normally relies on a variety of external signals, such as chemical,
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …

Many symbiotic relationships rely on the acquisition of microbial partners from the
environment. However, the mechanisms by which microbial symbionts find and colonize …

Many animals keep track of their angular heading over time while navigating through their
environment. However, a neural-circuit architecture for computing heading has not been …

In addition to their early-recognized functions in host defense and the clearance of apoptotic
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Chemotaxis of tumour cells and stromal cells in the surrounding microenvironment is an
essential component of tumour dissemination during progression and metastasis. This …

Stimuli that promote cell migration, such as chemokines, cytokines, and growth factors in
metazoans and cyclic AMP in Dictyostelium, activate signaling pathways that control …

Immune and inflammatory responses require leukocytes to migrate within and through the
vasculature, a process that is facilitated by their capacity to switch to a polarized morphology …