Determinants, maintenance, and function of organellar pH
SA Freeman, S Grinstein… - Physiological reviews, 2023 - journals.physiology.org
The protonation state of soluble and membrane-associated macromolecules dictates their
charge, conformation, and functional activity. In addition, protons (H+ or their equivalents) …
charge, conformation, and functional activity. In addition, protons (H+ or their equivalents) …
Mitochondrial cristae morphology reflecting metabolism, superoxide formation, redox homeostasis, and pathology
P Ježek, M Jabůrek, B Holendová… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Mitochondrial (mt) reticulum network in the cell possesses amazing
ultramorphology of parallel lamellar cristae, formed by the invaginated inner mitochondrial …
ultramorphology of parallel lamellar cristae, formed by the invaginated inner mitochondrial …
Cristae undergo continuous cycles of membrane remodelling in a MICOS‐dependent manner
AK Kondadi, R Anand, S Hänsch, J Urbach, T Zobel… - EMBO …, 2020 - embopress.org
The mitochondrial inner membrane can reshape under different physiological conditions.
How, at which frequency this occurs in living cells, and the molecular players involved are …
How, at which frequency this occurs in living cells, and the molecular players involved are …
Mitochondrial morphofunction in mammalian cells
EP Bulthuis, MJW Adjobo-Hermans… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: In addition to their classical role in cellular ATP production, mitochondria are of
key relevance in various (patho) physiological mechanisms including second messenger …
key relevance in various (patho) physiological mechanisms including second messenger …
A molecular rotor FLIM probe reveals dynamic coupling between mitochondrial inner membrane fluidity and cellular respiration
The inner mitochondrial membrane (IMM), housing components of the electron transport
chain (ETC), is the site for respiration. The ETC relies on mobile carriers; therefore, it has …
chain (ETC), is the site for respiration. The ETC relies on mobile carriers; therefore, it has …
Reversible Live‐Cell Labeling with Retro‐engineered HaloTags Enables Long‐Term High‐and Super‐Resolution Imaging
M Holtmannspötter, E Wienbeuker… - Angewandte Chemie …, 2023 - Wiley Online Library
Self‐labeling enzymes (SLE) such as the HaloTag have emerged as powerful tools in high
and super‐resolution fluorescence microscopy. Newly developed fluorogenic SLE …
and super‐resolution fluorescence microscopy. Newly developed fluorogenic SLE …
Collagen dynamics during the process of osteocyte embedding and mineralization
LA Shiflett, LAM Tiede-Lewis, Y Xie, Y Lu… - Frontiers in cell and …, 2019 - frontiersin.org
Bone formation, remodeling and repair are dynamic processes, involving cell migration,
ECM assembly, osteocyte embedding, and bone resorption. Using live-cell imaging, we …
ECM assembly, osteocyte embedding, and bone resorption. Using live-cell imaging, we …
[HTML][HTML] Inhibition of the mitochondrial ATPase function by IF1 changes the spatiotemporal organization of ATP synthase
V Weissert, B Rieger, S Morris, T Arroum… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Mitochondrial F 1 FO ATP synthase is the key enzyme for mitochondrial bioenergetics.
Dimeric F 1 F O-ATP synthase, is preferentially located at the edges of the cristae and its …
Dimeric F 1 F O-ATP synthase, is preferentially located at the edges of the cristae and its …
[HTML][HTML] Pigment-protein complexes are organized into stable microdomains in cyanobacterial thylakoids
A Strašková, G Steinbach, G Konert, E Kotabová… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Thylakoids are the place of the light-photosynthetic reactions. To gain maximal efficiency,
these reactions are conditional to proper pigment-pigment and protein-protein interactions …
these reactions are conditional to proper pigment-pigment and protein-protein interactions …
Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes
V Göser, N Sander, M Schulte, F Scharte… - Nature …, 2023 - nature.com
The facultative intracellular pathogen Salmonella enterica remodels the host endosomal
system for survival and proliferation inside host cells. Salmonella resides within the …
system for survival and proliferation inside host cells. Salmonella resides within the …