The bone matrix plays an indispensable role in the human body, and its unique
biomechanical and mechanobiological properties have received much attention. The bone …

Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …

Objectives Examine whether osteoarthritis (OA) progression can be delayed by
halofuginone in anterior cruciate ligament transection (ACLT) rodent models. Methods 3 …

Stem cell research has been a popular topic in the past few decades. This review aims to
discuss factors that help regulate, induce, and enhance mesenchymal stem cell (MSC) …

The adult human skeleton is a multifunctional organ undergoing constant remodeling
through the opposing activities of the bone-resorbing osteoclast and the bone-forming …

Human mesenchymal stem/stromal cell (hMSC)-based cell therapies are promising for
treating a variety of diseases. The unique immunomodulatory properties of hMSCs have …

Carbohydrates, fats, and proteins are the underlying energy sources for animals and are
catabolized through specific biochemical cascades involving numerous enzymes. The …

The significant biochemical and physiological effects of psychological stress are beginning
to be recognized as exacerbating common diseases, including osteoporosis. This review …

Neurological diseases, particularly in the context of aging, have serious impacts on quality of
life and can negatively affect bone health. The brain-bone axis is critically important for …

Since the original description of spondyloarthritis 50 years ago, results have demonstrated
similarities and differences between ankylosing spondylitis (AS) and axial psoriatic arthritis …