Background: Rheumatoid factor (RF) and autoantibodies against cyclic citrullinated peptide
(CCP) are markers that might help physicians diagnose rheumatoid arthritis. Purpose: To …

Objective: To evaluate the two generations of anti-cyclic citrullinated protein (CCP)
antibodies as a diagnostic marker of rheumatoid arthritis (RA) and as a predictor of future …

Objective To map the antibody response to human citrullinated α‐enolase, a candidate
autoantigen in rheumatoid arthritis (RA), and to examine cross‐reactivity with bacterial …

Increasingly, assays for the detection of anti-citrullinated peptide antibodies (ACPA) are
used in RA diagnosis. This review summarizes the biologic basis and development of ACPA …

The etiology of autoimmune diseases is due to a combination of genetic predisposition and
environmental factors that alter the expression of immune regulatory genes through various …

Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative,
depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti …

This systematic review assesses the current status of anti‐cyclic citrullinated peptide (anti‐
CCP) and rheumatoid factor (RF) tests in the diagnosis and prognosis of rheumatoid arthritis …

Rheumatoid arthritis is both common and chronic, with significant consequences for multiple
organ systems. Better understanding of its pathophysiology has led to the development of …

Individuals with high anti-citrullinated protein antibody (ACPA) titers have an increased risk
of developing rheumatoid arthritis (RA). Although our knowledge of the generation and …

One of the most common autoimmune diseases is rheumatoid arthritis (RA), affecting 0.5–
1% of the population. This systemic disease is marked by chronic inflammation of synovial …