J‐Aggregation Strategy toward Potentiated NIR‐II Fluorescence Bioimaging of Molecular Fluorophores

X Hu, C Zhu, F Sun, Z Chen, J Zou, X Chen… - Advanced …, 2024 - Wiley Online Library
Molecular fluorophores emitting in the second near‐infrared (NIR‐II, 1000–1700 nm)
window with strong optical harvesting and high quantum yields hold great potential for in …

[HTML][HTML] Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications

N Singh, J Kim, J Kim, K Lee, Z Zunbul, I Lee, E Kim… - Bioactive materials, 2023 - Elsevier
Nanomedicines for drug delivery and imaging-guided cancer therapy is a rapidly growing
research area. The unique properties of nanomedicines have a massive potential in solving …

Activation of Pyroptosis Using AIEgen-Based sp2 Carbon-Linked Covalent Organic Frameworks

L Zhang, SC Wan, J Zhang, MJ Zhang… - Journal of the …, 2023 - ACS Publications
Covalent organic frameworks (COFs) have emerged as a promising class of crystalline
porous materials for cancer phototherapy, due to their exceptional characteristics, including …

Integration of AIEgens into covalent organic frameworks for pyroptosis and ferroptosis primed cancer immunotherapy

L Zhang, A Song, QC Yang, SJ Li, S Wang… - Nature …, 2023 - nature.com
Immunogenic programmed cell death, such as pyroptosis and ferroptosis, efficiently induces
an acute inflammatory response and boosts antitumor immunity. However, the exploration of …

Designing Single‐Atom Active Sites on sp2‐Carbon Linked Covalent Organic Frameworks to Induce Bacterial Ferroptosis‐Like for Robust Anti‐Infection Therapy

B Sun, X Wang, Z Ye, J Zhang, X Chen… - Advanced …, 2023 - Wiley Online Library
With the threat posed by drug‐resistant pathogenic bacteria, developing non‐antibiotic
strategies for eradicating clinically prevalent superbugs remains challenging. Ferroptosis is …

Macrocycle‐Based Covalent Organic Frameworks

Y Yuan, KT Bang, R Wang, Y Kim - Advanced Materials, 2023 - Wiley Online Library
Macrocycles with well‐defined cavities and the ability to undergo supramolecular
interactions are classical materials that have played an essential role in materials science …

Nanoplatforms based on covalent organic frameworks (COFs) for biomedical applications

S Liang, MH Li, M Qi, L Wang, YW Yang - Chemistry of Materials, 2023 - ACS Publications
Covalent organic frameworks (COFs) make up an emerging class of crystalline porous
materials mainly composed of light elements in the form of dynamic covalent bonds. Owing …

Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity

Y Liu, R Niu, H Zhao, Y Wang, S Song… - Journal of the …, 2024 - ACS Publications
The extracellular matrix (ECM) in the tumor microenvironment (TME) and upregulated
immune checkpoints (ICs) on antitumor immune cells impede the infiltration and killing effect …

A biodegradable covalent organic framework for synergistic tumor therapy

WY Li, JJ Wan, JL Kan, B Wang, T Song, Q Guan… - Chemical …, 2023 - pubs.rsc.org
Stimulus-responsive biodegradable nanocarriers with tumor-selective targeted drug delivery
are critical for cancer therapy. Herein, we report for the first time a redox-responsive disulfide …

Nanoscale covalent organic framework with staggered stacking of phthalocyanines for mitochondria-targeted photodynamic therapy

J Liu, DW Kang, Y Fan, GT Nash, X Jiang… - Journal of the …, 2023 - ACS Publications
Phthalocyanine photosensitizers (PSs) have shown promise in fluorescence imaging and
photodynamic therapy (PDT) of malignant tumors, but their practical application is limited by …