The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

The availability of sensors able to rapidly detect SARS-CoV-2 directly in biological fluids in a
single step would allow performing massive diagnostic testing to track in real time and …

For fluorogenic probes, Förster resonance energy transfer (FRET) is one of the most widely
used mechanisms to realize the detection of biochemical activities. Dark quenchers relax …

Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …

Aptamers are nucleic acid-based affinity reagents that have been incorporated into a variety
of molecular sensor formats. However, many aptamer sensors exhibit insufficient sensitivity …

DNA and RNA oligomers are used in a myriad of diverse biological and biochemical
experiments. These oligonucleotides are designed to have unique biophysical, chemical …

The breakthroughs in single molecule spectroscopy of the last decade and the recent
advances in super resolution microscopy have boosted the popularity of cyanine dyes in …

Recent years have seen great advances in the development of synthetic self-assembling
molecular systems. Designing out-of-equilibrium architectures, however, requires a more …

DNA is used to construct synthetic systems that sense, actuate, move and compute. The
operation of many dynamic DNA devices depends on toehold-mediated strand …