Osteoarthritis year in review 2023: genetics, genomics, and epigenetics

A Waheed, MF Rai - Osteoarthritis and Cartilage, 2024 - Elsevier
Objective To elucidate the scientific advances made in the last 12 months within the realm of
osteoarthritis genetics, genomics, and epigenetics. This review paper highlights major …

Differentially‐regulated miRNAs in COVID‐19: A systematic review

W Ahmad, B Gull, J Baby, NG Panicker… - Reviews in Medical …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is responsible for
coronavirus disease of 2019 (COVID‐19) that infected more than 760 million people …

miR-140-5p protects cartilage progenitor/stem cells from fate changes in knee osteoarthritis

Y Chen, H Huang, W Zhong, L Li, Y Lu, H Si - International …, 2023 - Elsevier
Cartilage progenitor/stem cells (CPCs) are promising seed cells for cartilage regeneration,
but their fate changes and regulatory mechanisms in osteoarthritis (OA) pathogenesis …

SP1‑mediated ADAMTS5 transcription promotes IL‑1β‑induced chondrocyte injury via Wnt/β‑catenin pathway in osteoarthritis

X Hao, X Wu - Molecular Medicine Reports, 2024 - spandidos-publications.com
Osteoarthritis (OA) is a chronic disease that involves chondrocyte injury. ADAMTS5 has
been confirmed to mediate chondrocyte injury and thus regulate OA progression, but its …

Role of signal transduction pathways in IL‐1β‐induced apoptosis: Pathological and therapeutic aspects

P Wang, H Qian, M Xiao, J Lv - Immunity, Inflammation and …, 2023 - Wiley Online Library
Abstract Background Interleukin‐1β (IL‐1β) is a pro‐inflammatory cytokine mainly produced
by monocytes and macrophages with a wide range of biological effects. Evidence has …

Sustained released of microRNA-99b-3p abundant exosomes derived from adipose stem cell encapsulated with hydrogel microparticles (HMPs) for long-term …

Z Yin, S Pan, C Shi, G Wu, Y Feng, C Qin, J Zhang… - 2023 - researchsquare.com
Adipose derived stem cells (ADSCs) have the potential to attenuate osteoarthritis (OA);
however, complications such as immune rejection and tumour formation limit their …