Correlative microscopy, the integration of two or more microscopy techniques performed on
the same sample, produces results that emphasize the strengths of each technique while …

We review the emerging method of super-resolved cryogenic correlative light and electron
microscopy (srCryoCLEM). Super-resolution (SR) fluorescence microscopy and cryogenic …

We introduce MINFLUX, a concept for localizing photon emitters in space. By probing the
emitter with a local intensity minimum of excitation light, MINFLUX minimizes the …

We introduce an interferometric single-molecule localization method for super-resolution
fluorescence microscopy. Fluorescence molecules are located by the intensities of multiple …

Sample fixation by vitrification is critical for the optimal structural preservation of
biomolecules and subsequent high-resolution imaging by cryo-correlative light and electron …

Controlling the propagation and coupling of light to sub-wavelength antennas is a crucial
prerequisite for many nanoscale optical devices. Recently, the main focus of attention has …

Correlative light and electron microscopy (CLEM) has become a powerful tool in life
sciences. Particularly cryo‐CLEM, the combination of fluorescence cryo‐microscopy (cryo …

G protein–coupled receptors (GPCRs), including dopamine receptors, represent a group of
important pharmacological targets. An increased formation of dopamine receptor D2 …

We introduce a super-resolution technique for fluorescence cryo-microscopy based on
photoswitching of standard genetically encoded fluorescent marker proteins in intact …

Super-resolved cryogenic correlative light and electron tomography is an emerging method
that provides both the single-molecule sensitivity and specificity of fluorescence imaging …