Although the study of germ cell death is arguably still in its infancy as a field, several recent
breakthroughs have provided the fodder for a story, replete with episodes of apparent mass …

All sexually reproducing organisms arise from gametes, sembly of pole plasm material at the
posterior pole of highly specialized cells that together initiate constructhe oocyte …

The testes produce the male gametes and the male sexual hormones (androgens). The term
spermatogenesis describes and includes all the processes involved in the production of …

Oncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin (IL)-6
subfamily. Among the family members, OSM is most closely related to leukemia inhibitory …

In all animals information is passed from parent to offspring via the germline, which
segregates from the soma early in development and undergoes a complex developmental …

Leukemia-inhibitory factor (LIF) is a pleiotropic cytokine expressed by multiple tissue types.
The LIF receptor shares a common gp130 receptor subunit with the IL-6 cytokine …

Leukaemia inhibitory factor (LIF) is one of the most important cytokines in the reproductive
tract. Without expression of LIF in the uterus, implantation of a blastocyst cannot begin. Yet …

Inductive signals cause conversion of mesenchyme into epithelia during the formation of
many organs. Yet a century of study has not revealed the inducing molecules. Using a …

Oncostatin M (OSM) is a multifunctional cytokine that belongs to the interleukin 6 (IL-6)
family. As OSM is expressed in adult as well as embryonic hematopoietic tissues, OSM has …

Mouse primordial germ cells (PGCs) arrive at the urogenital ridge (UGR) at around 10.5
days postcoitum (dpc). They proliferate until around 13.5 dpc, then enter into meiosis in the …