Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

The enlargement and species-specific elaboration of the cerebral neocortex during
evolution holds the secret to the mental abilities of humans; however, the genetic origin and …

The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …

Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …

In recent years, tremendous progress has been made in understanding the mechanisms
underlying the specification of projection neurons within the mammalian neocortex. New …

The cerebral neocortex is segregated into six horizontal layers, each containing unique
populations of molecularly and functionally distinct excitatory projection (pyramidal) neurons …

Pyramidal neurons of the neocortex can be subdivided into two major groups: deep-(DL)
and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA …

It is controversial whether mouse extrastriate cortex has a “simple” organization in which
lateral primary visual cortex (V1) is adjoined by a single area V2 or has a “complex” …

This review aims to provide examples of how both comparative and genetic analyses
contribute to our understanding of the rules for cortical development and evolution. Genetic …

The cerebral cortex has a central role in cognitive and emotional processing. As such,
understanding the mechanisms that govern its development and function will be central to …