Cancer cells continuously rewire their metabolism to fulfill their need for rapid growth and
survival while subject to changes in environmental cues. Thus, a vital component of a cancer …

Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by a
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …

A well-established role of cyclic GMP-AMP synthase (cGAS) is the recognition of cytosolic
DNA, which is linked to the activation of host defense programs against pathogens via …

Mitochondrial components have been abundantly detected in bone matrix, implying that they
are somehow transported extracellularly to regulate osteogenesis. Here, we demonstrate …

Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance
imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia …

Mitochondria are critical for metabolic homeostasis of the liver, and their dysfunction is a
major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a …

Revascularization plays a critical role in the healing of diabetic wounds. Accumulation of
advanced glycation end products (AGEs) and refractory multidrug resistant bacterial …

In the past mitochondria were considered as the “powerhouse” of cell, since they generate
more than 90% of ATP in aerobic conditions through the oxidative phosphorylation …

The importance of mitochondrial dynamics, the physiological process of mitochondrial fusion
and fission, in regulating diverse cellular functions and cellular fitness has been well …

Distinct morphologies of the mitochondrial network support divergent metabolic and
regulatory processes that determine cell function and fate,–. The mechanochemical GTPase …