Current and future strategies for targeting the endothelin pathway in cardiovascular disease

GR Abraham, TL Williams, JJ Maguire… - Nature Cardiovascular …, 2023 - nature.com
Abstract The first endothelin (ET)-1 receptor antagonist was approved for clinical use over
20 years ago, but to date this class of compounds has been limited to treating pulmonary …

Novel therapeutic strategies in heart failure in adult congenital heart disease: of medicines and devices

S Vaikunth, S Sundaravel, J Saef… - Current Heart Failure …, 2023 - Springer
Abstract Purpose of Review This paper reviews the latest literature on the growing field of
heart failure in the adult congenital heart disease population. Recent Findings After …

Pulmonary Hypertension in Adults with Congenital Heart Disease

K Dimopoulos, A Constantine - … Fetal, Pediatric, and Adult Congenital Heart …, 2024 - Springer
Pulmonary hypertension (PH) complicates congenital heart disease (CHD) in up to 10% of
cases and impacts quality of life and survival of these patients. Different forms of PH related …

[HTML][HTML] A retrospective review of sildenafil in the Australia and New Zealand Fontan registry: indications and treatment responses

P Rueter, M O'Dell, D Celermajer, C O'Donnell… - International Journal of …, 2024 - Elsevier
Structured Abstract Introduction Rates of morbidity and mortality are high in the setting of
Fontan physiology and effective medical therapies are not well-established. Clinical trials …

Managing the Pulmonary Circulation

A Constantine, P Clift - Univentricular Congenital Heart Defects and the …, 2024 - Springer
The Fontan circulation does not have a sub-pulmonary pump and therefore the pulmonary
circulation is key to the optimal functioning of the Fontan circuit. Pulmonary blood flow may …

Komplikácie u pacientov s fontanovskou cirkuláciou.

M Záhorec - Cardiology Letters, 2023 - search.ebscohost.com
Zahorec M. Complications in patients with Fontan circulation. Cardiology Lett. 2023; 32 (2):
115–128 Abstract. It has been 50 years since the Fontan operation was introduced and it is …