The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

The physiological role of the neurotrophin nerve growth factor (NGF) has been
characterized, since its discovery in the 1950s, first in the sensory and autonomic nervous …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin, which plays an important role in
the central nervous system, and systemic or peripheral inflammatory conditions, such as …

Depression and suicidal behavior have recently been shown to be associated with
disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) …

Nerve growth factor (NGF) is the firstly discovered and best characterized neurotrophic
factor, known to play a critical protective role in the development and survival of sympathetic …

Improving clinical tests are allowing us to more precisely classify autism spectrum disorders
and diagnose them at earlier ages. This raises the possibility of earlier and potentially more …

We have identified, cultured, characterized, and propagated adult pluripotent stem cells
(PSC) from a subset of human peripheral blood monocytes. These cells, which in …

Background Brain-derived neurotrophic factor is implicated in the pathophysiology of major
depressive disorder and suicide. Both are partly caused by early life adversity, which …

The cortical neuropathology of schizophrenia includes neuronal atrophy, decreased
neuropil, and alterations in neuronal density. Taken together with evidence of decreased …

Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the
potential to affect vision, and can even be fatal in some children. While the tumor can be …