Publisher Summary 1, 2, 4-Triazolo [1, 5-a] pyrimidines (TPs) play an important role in
pharmaceutics, agrochemistry, photography, and other fields. They attract attention in …

The present review focuses on the synthesis of two heteroatoms containing sixmembered
heterocyclic compounds, ie, pyrimidine. In this review, a number of pyrimidine derivatives …

This Review describes the existing synthetic approaches for the solid-phase synthesis (SPS)
of differently substituted and fused pyrimidine derivatives. These synthetic strategies are …

According to WHO, infectious diseases are still a significant threat to public health. The
combine effects of antibiotic resistance, immunopressure, and mutations within the bacterial …

To search for new cruzain inhibitors, the synthesis of a series of novel 2-(N′-
benzylidenehydrazino)-4-trifluoromethyl-pyrimidines in a convergent manner is presented …

The triazolopyrimidine natural product essramycin (1) was synthesized without the use of
protecting groups via a two-step reaction scheme involving a 3-amino-1, 2, 4-triazole …

We report a practical high-yield synthesis of 5, 7-disubstituted-1, 2, 4-triazolo [1, 5-a]
pyrimidines using a base-assisted cyclocondensation of chalcone and 1, 2, 4-triazol-3 …

Abstract The interaction of 2-ethoxymethylidene-3-oxo esters and their analogues with 5-
aminotetrazole is an efficient synthetic approach to novel azaheterocycles. 2 …

(Ethoxymethylidene)-3-oxo carboxylic acid esters reacted with tetrazol-5-amine to give ethyl
4-alkyl-2-azidopyrimidine-5-carboxylates capable of undergoing subsequent nucleophilic …

The chemotype of arylsulfonamide derivatives of cyclic arylguanidines is a source of
molecules with valuable biological activities, including antimicrobial and antitumor …