The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …

MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …

MicroRNAs (miRNAs) are small noncoding RNAs that typically inhibit the translation and
stability of messenger RNAs (mRNAs), controlling genes involved in cellular processes such …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

MicroRNAs (miRNAs) are small RNAs that control gene expression through silencing of
target mRNAs. Mature miRNAs are processed from primary miRNA transcripts by the …

The abnormal autophagy is associated with a variety of cardiovascular diseases. Long
noncoding RNAs (lncRNAs) are emerging as new factors in gene regulation, but how …

Small RNA molecules regulate eukaryotic gene expression during development and in
response to stresses including viral infection. Specialized ribonucleases and RNA-binding …

MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …

Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

Since their discovery almost two decades ago, microRNAs (miRNAs) have been shown to
function by post-transcriptionally regulating protein accumulation. Understanding how …