By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …

Objective: Several published studies have investigated the association between the−
308G/A (rs1800629) polymorphism in the tumor necrosis factor-α (TNF-α) gene and the risk …

Cardiovascular diseases (CVD) are group of complex and multifactorial pathologies, in
which interleukin-6 (IL-6) gene polymorphisms have been associated with several …

Background “Quantile-dependent expressivity” occurs when the effect size of a genetic
variant depends upon whether the phenotype (eg, C-reactive protein, CRP) is high or low …

Background Cytokine storm is known to impact the prognosis of coronavirus disease 2019
(COVID-19), since pro-inflammatory cytokine variants are associated with cytokine storm. It …

Osteoarthritis (OA) is one of the most common musculoskeletal diseases of adults
worldwide. Inflammation plays a crucial part in OA pathology, but role of cytokines is still …

The economic and social burden associated with Chagas disease morbidity and mortality is
regrettably large in Latin America causing more deaths than does any other parasitic …

Association analysis between ARG1 gene polymorphisms and idi... : Medicine Association
analysis between ARG1 gene polymorphisms and idiopathic dilated cardiomyopathy : Medicine …

The issue that genetic polymorphism of tumor necrosis factor-α (TNF-α) is associated with
dilated cardiomyopathy (DCM) is debatable. We sought to investigate the potential role of …

Background: Dilated cardiomyopathy (DCM) is a primary myocardial disease characterized
by left ventricular or biventricular dilatation and impaired myocardial contractility. IL-6 is a …