RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Alternative splicing of mRNA precursors is a nearly ubiquitous and extremely flexible point of
gene control in humans. It provides cells with the opportunity to create protein isoforms of …

Alternative splicing modulates the expression of many oncogene and tumor-suppressor
isoforms. We have tested whether some alternative splicing factors are involved in cancer …

Eukaryotic cells express a large variety of RNA binding proteins (RBPs), with diverse
affinities and specificities towards target RNAs. These proteins play a crucial role in almost …

Alternative splicing of mRNA precursors enables one gene to produce multiple protein
isoforms with differing functions. Under normal conditions, this mechanism is tightly …

More than 95% of the 20,000 to 25,000 transcribed human genes undergo alternative RNA
splicing, which increases the diversity of the proteome. Isoforms derived from the same gene …

RNA interference (RNAi) is a powerful gene-silencing process that holds great promise in
the field of cancer therapy. The discovery of RNAi has generated enthusiasm within the …