Despite the continuous advancement in neurosciences as well as in the knowledge of
human behaviors pathophysiology, currently suicide represents a puzzling challenge. The …

Aggression and deficient cognitive control problems are widespread in psychiatric disorders,
including major depressive disorder (MDD). These abnormalities are known to contribute …

Investigation of the neural mechanisms underlying social hierarchy requires a reliable and
effective behavioral test. The tube test is a simple and robust behavioral assay that we …

Purpose: It is revealed that Xiaoyaosan could reduce glutamate level in the hippocampus of
depressed rats, whose metabolism leads to the pathophysiology of depression. However …

Chronic exposure to stressful environment is a key risk factor contributing to the
development of depression. However, the mechanisms involved in this process are still …

Major depressive disorder (MDD) is a prevalent psychiatric disorder that brings great harm
and burden to both patients and society. This study aimed to examine the effects of whole …

Aim To investigate the effects of crocin on depression induced by chronic restraint stress
(CRS) in mice. Methods Depression model was established induced by CRS. All mice were …

Worldwide, suicide is a leading cause of death. Although a sizable proportion of deaths by
suicide may be preventable, it is well documented that despite major governmental and …

INTRODUCTION Coping with negative experience is essential for survival. Animals must
quickly recognize a harmful situation, produce an adequate response, and learn its context …

The establishment and maintenance of social dominance are critical for social stability and
the survival and health of individual animals. Stress lead to depression and a decrease in …