Lung imaging using conventional 1H MRI presents great challenges because of the low
density of lung tissue, lung motion and very fast lung tissue transverse relaxation (typical T2 …

Purpose The goal of this work was to investigate lung morphological changes associated
with chronic obstructive pulmonary disease (COPD) using hyperpolarized 129Xe diffusion …

The 3He lung morphometry technique, based on MRI measurements of hyperpolarized 3He
gas diffusion in lung airspaces, provides unique information on the lung microstructure at the …

Purpose Hyperpolarized 129Xe MRI depicting 3D ventilation, interstitial barrier uptake, and
transfer to red blood cells (RBCs) has emerged as a powerful new means of detecting …

In this study, the signal‐to‐noise ratio of hyperpolarized 129Xe human lung magnetic
resonance imaging was compared at 1.5 T and 3 T. Experiments were performed at both B0 …

Purpose To evaluate T2,, and signal‐to‐noise ratio (SNR) for hyperpolarized helium‐3
(3He) MRI of the human lung at three magnetic field strengths ranging from 0.43 T to 1.5 T …

In this paper we demonstrate that gradient echo MRI with hyperpolarized 3He gas can be
used for simultaneously extracting in vivo information about lung ventilation properties …

Several characteristics of hyperpolarized gases relevant to the design of magnetic
resonance acquisitions differ substantially from those for water or lipid protons in biological …

Pulmonary diseases are one of the leading causes of death and contribute to major
healthcare cost in the United States. However, clinical treatment of these diseases has long …

Purpose: To evaluate T2, TÃ 2, and signal-to-noise ratio (SNR) for hyperpolarized helium-3
(3He) MRI of the human lung at three magnetic field strengths ranging from 0.43 T to 1.5 T …