Dopaminergic medications used in the treatment of patients with Parkinson's disease are
associated with motor and non-motor behavioural side-effects, such as dyskinesias and …

Tourette syndrome is a chronic neurodevelopmental disorder characterised by motor and
phonic tics that can substantially diminish the quality of life of affected individuals. Evaluating …

Background Quantitative susceptibility mapping (QSM) and R2* relaxation rate mapping
have demonstrated increased iron deposition in the substantia nigra of patients with …

The existence of so-called 'basic emotions' and their defining attributes represents a long
lasting and yet unsettled issue in psychology. Recently, neuroimaging evidence, especially …

Age has a major effect on brain volume. However, the normative studies available are
constrained by small sample sizes, restricted age coverage and significant methodological …

Brain lesions are a rare cause of tic disorders. However, they can provide uniquely causal
insights into tic pathophysiology and can also inform on possible neuromodulatory …

The benefit of deep brain stimulation (DBS) in controlling the motor symptoms of Parkinson's
disease is well established, however, the impact on the non-motor symptoms (NMS) remains …

Brain subcortical structures are paramount in many cognitive functions and their aberrations
during infancy are predisposed to various neurodevelopmental and neuropsychiatric …

Parkinson's disease (PD) is a progressive neurodegenerative disease which affects millions
of population worldwide. It is characterized by motor symptoms such as excessive tremor …

Apathy is a debilitating and under-recognized condition that has a significant impact in many
neurodegenerative disorders. In Parkinson's disease, it is now known to contribute to worse …