[HTML][HTML] Single-molecular Förster resonance energy transfer measurement on structures and interactions of biomolecules
Y Qiao, Y Luo, N Long, Y Xing, J Tu - Micromachines, 2021 - mdpi.com
Single-molecule Förster resonance energy transfer (smFRET) inherits the strategy of
measurement from the effective “spectroscopic ruler” FRET and can be utilized to observe …
measurement from the effective “spectroscopic ruler” FRET and can be utilized to observe …
[HTML][HTML] Structure-specific endonucleases and the resolution of chromosome underreplication
B Falquet, U Rass - Genes, 2019 - mdpi.com
Complete genome duplication in every cell cycle is fundamental for genome stability and
cell survival. However, chromosome replication is frequently challenged by obstacles that …
cell survival. However, chromosome replication is frequently challenged by obstacles that …
Scanning two-dimensional fluorescence lifetime correlation spectroscopy: Conformational dynamics of DNA Holliday junction from microsecond to subsecond
W Heo, K Hasegawa, K Okamoto, Y Sako… - The Journal of …, 2022 - ACS Publications
Single-molecule Förster resonance energy transfer (smFRET) is widely utilized to
investigate the structural heterogeneity and dynamics of biomolecules. However, it has been …
investigate the structural heterogeneity and dynamics of biomolecules. However, it has been …
[HTML][HTML] Implementing fluorescence enhancement, quenching, and FRET for investigating flap endonuclease 1 enzymatic reaction at the single-molecule level
Abstract Flap endonuclease 1 (FEN1) is an important component of the intricate molecular
machinery for DNA replication and repair. FEN1 is a structure-specific 5′ nuclease that …
machinery for DNA replication and repair. FEN1 is a structure-specific 5′ nuclease that …
Single bacterial resolvases first exploit, then constrain intrinsic dynamics of the Holliday junction to direct recombination
Homologous recombination forms and resolves an entangled DNA Holliday Junction (HJ)
crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity …
crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity …
Canonical and novel non-canonical activities of the Holliday junction resolvase Yen1
R Carreira, FJ Aguado, V Hurtado-Nieves… - Nucleic Acids …, 2022 - academic.oup.com
Yen1 and GEN1 are members of the Rad2/XPG family of nucleases that were identified as
the first canonical nuclear Holliday junction (HJ) resolvases in budding yeast and humans …
the first canonical nuclear Holliday junction (HJ) resolvases in budding yeast and humans …
Molecular Insight into the Structural Dynamics of Holliday Junctions Modulated by Integration Host Factor
F Islam, PP Mishra - The Journal of Physical Chemistry B, 2024 - ACS Publications
The integration host factor (IHF) in Escherichia coli is a nucleoid-associated protein with
multifaceted roles that encompass DNA packaging, viral DNA integration, and …
multifaceted roles that encompass DNA packaging, viral DNA integration, and …
[HTML][HTML] GEN1 as a risk factor for human congenital anomalies of the kidney and urinary tract
X Du, C Wang, J Liu, M Yu, H Ju, S Xue, Y Li, J Liu… - Human Genomics, 2024 - Springer
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are prevalent
birth defects. Although pathogenic CAKUT genes are known, they are insufficient to reveal …
birth defects. Although pathogenic CAKUT genes are known, they are insufficient to reveal …
Engineering of the Lrp/AsnC‐type transcriptional regulator DecR as a genetically encoded biosensor for multilevel optimization of L‐cysteine biosynthesis pathway in …
Z Zhou, Z Li, Y Zhong, S Xu, Z Li - Biotechnology and …, 2024 - Wiley Online Library
L‐cysteine is an important sulfur‐containing amino acid being difficult to produce by
microbial fermentation. Due to the lack of high‐throughput screening methods, existing …
microbial fermentation. Due to the lack of high‐throughput screening methods, existing …
[HTML][HTML] Decoding the structural dynamics and conformational alternations of DNA secondary structures by single-molecule FRET microspectroscopy
D Bandyopadhyay, PP Mishra - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
In addition to the canonical double helix form, DNA is known to be extrapolated into several
other secondary structural patterns involving themselves in inter-and intramolecular type …
other secondary structural patterns involving themselves in inter-and intramolecular type …