Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022 - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a chronic complication that affects people of all ages. The increased
prevalence of diabetes worldwide has led to the development of several synthetic drugs to …

Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis

X Ou, H Wang, H Tie, J Liao, Y Luo, W Huang… - Journal of …, 2023 - Springer
Background Plant-derived exosomes-like nanovesicles (PDENs) have been found to be
advantageous in disease treatment and drug delivery, but research on their biogenesis …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

Emerging mechanistic insights into the regulation of specialized metabolism in plants

LV Méteignier, HW Nützmann, N Papon, A Osbourn… - Nature plants, 2023 - nature.com
Plants biosynthesize a broad range of natural products through specialized and species-
specific metabolic pathways that are fuelled by core metabolism, together forming a …

More than a Catharanthus plant: a multicellular and pluri-organelle alkaloid-producing factory

N Kulagina, LV Méteignier, N Papon… - Current Opinion in Plant …, 2022 - Elsevier
Plants represent a huge reservoir of natural products. A broad series of these compounds
now find application for human health. In this respect, the monoterpene indole alkaloids …

Emerging innovations in vincristine-encapsulated nanoparticles: Pioneering a new era in oncological therapeutics

S Bakhshi, A Shoari, P Alibolandi, M Ganji… - Journal of Drug Delivery …, 2024 - Elsevier
This encompassing review article synthesizes multiple studies and methods all revolving
around the innovative use of nanoparticles (NPs) for Vincristine (VCR) delivery as a cancer …

Genus Rauvolfia: A review of its ethnopharmacology, phytochemistry, quality control/quality assurance, pharmacological activities and clinical evidence

S Kumar, D Kumari, B Singh - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The plants are from the genus Rauvolfia Plum. ex
L.(Apocynaceae), which is represented by 74 species with many synonyms, and distributed …

Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Medicinal plants used for eye conditions in mexico—A review

A Salazar-Gómez, AA Velo-Silvestre… - Pharmaceuticals, 2023 - mdpi.com
Medicinal plants have been historically significant for treating common human diseases in
Mexico. Although some ethnobotanical research exists, limited ethnomedicinal data has …