Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …

The outbreak of coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) infection, has emerged in China in December 2019 …

Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …

The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …

Interleukin-7 (IL-7), a molecule known for its growth-promoting effects on progenitors of B
cells, remains one of the most extensively studied cytokines. It plays a vital role in health …

Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

The balance between Th17 cells and regulatory T cells (Tregs) has emerged as a prominent
factor in regulating autoimmunity and cancer. Th17 cells are vital for host defense against …

Interleukin (IL)-17 is the founding member of a novel family of inflammatory cytokines. While
the proinflammatory properties of IL-17 are key to its host-protective capacity, unrestrained IL …

The pathogenesis of psoriasis can be explained by dysregulation of immunological cell
function as well as keratinocyte proliferation/differentiation. Recently, the immunological …