Chlorthalidone for hypertension in advanced chronic kidney disease
R Agarwal, AD Sinha, AE Cramer… - … England Journal of …, 2021 - Mass Medical Soc
Background Little evidence has been available to support the use of thiazide diuretics to
treat hypertension in patients with advanced chronic kidney disease. Methods We randomly …
treat hypertension in patients with advanced chronic kidney disease. Methods We randomly …
Hypertension in chronic kidney disease—treatment standard 2023
PI Georgianos, R Agarwal - Nephrology Dialysis Transplantation, 2023 - academic.oup.com
Hypertension is very common and remains often poorly controlled in patients with chronic
kidney disease (CKD). Accurate blood pressure (BP) measurement is the essential first step …
kidney disease (CKD). Accurate blood pressure (BP) measurement is the essential first step …
Resistant hypertension in chronic kidney disease (CKD): prevalence, treatment particularities, and research agenda
PI Georgianos, R Agarwal - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review To explore the prevalence, treatment particularities, and
research agenda in the management of resistant hypertension among patients with chronic …
research agenda in the management of resistant hypertension among patients with chronic …
Effect of finerenone on ambulatory blood pressure in chronic kidney disease in type 2 diabetes
R Agarwal, LM Ruilope, G Ruiz-Hurtado… - Journal of …, 2023 - journals.lww.com
Objective: Finerenone is a selective nonsteroidal mineralocorticoid receptor antagonist with
a short half-life. Its effects on cardiorenal outcomes were thought to be mediated primarily …
a short half-life. Its effects on cardiorenal outcomes were thought to be mediated primarily …
The Indian chronic kidney disease (ICKD) study: baseline characteristics
Background Chronic kidney disease (CKD) is an important cause of morbidity and mortality
worldwide. There is a lack of information on epidemiology and progression of CKD in low …
worldwide. There is a lack of information on epidemiology and progression of CKD in low …
Efficacy and safety of ocedurenone: subgroup analysis of the BLOCK-CKD study
GL Bakris, YF Yang, JM McCabe, JR Liu… - American Journal of …, 2023 - academic.oup.com
Abstract BACKGROUND Ocedurenone (KBP-5074), a nonsteroidal mineralocorticoid
receptor antagonist, is documented to lower blood pressure in patients with stage 3b/4 …
receptor antagonist, is documented to lower blood pressure in patients with stage 3b/4 …
Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1‐Drp1 signalling pathway
Z Chen, W Liang, J Hu, Z Zhu, J Feng, Y Ma… - Cell …, 2022 - Wiley Online Library
Objectives Increasing evidence suggests that mitochondrial dysfunction is the key driver of
angiotensin II (Ang II)‐induced kidney injury. This study was designed to investigate whether …
angiotensin II (Ang II)‐induced kidney injury. This study was designed to investigate whether …
Adherence to the Kidney Disease: Improving Global Outcomes CKD guideline in nephrology practice across countries
Introduction The uptake of the Kidney Disease: Improving Global Outcomes (KDIGO) 2012
chronic kidney disease (CKD) Guideline is not fully described in real-world nephrology …
chronic kidney disease (CKD) Guideline is not fully described in real-world nephrology …
Associations with age and glomerular filtration rate in a referred population with chronic kidney disease: methods and baseline data from a UK multicentre cohort study …
MW Taal, B Lucas, P Roderick… - Nephrology Dialysis …, 2023 - academic.oup.com
Background Chronic kidney disease (CKD) is common but heterogenous and is associated
with multiple adverse outcomes. The National Unified Renal Translational Research …
with multiple adverse outcomes. The National Unified Renal Translational Research …
International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in Western Europe
Populations in the high-income countries of Western Europe are aging due to increased life
expectancy. As the prevalence of diabetes and obesity has increased, so has the burden of …
expectancy. As the prevalence of diabetes and obesity has increased, so has the burden of …