Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

Natural antifungal peptides/proteins as model for novel food preservatives

T Thery, KM Lynch, EK Arendt - … in food science and food safety, 2019 - Wiley Online Library
A large range of ingredients for food and food products are subject to fungal contamination,
which is a major cause of destruction of crops, exposure of animals and humans to invasive …

Gold-nanoparticles coated with the antimicrobial peptide esculentin-1a (1-21) NH2 as a reliable strategy for antipseudomonal drugs

B Casciaro, M Moros, S Rivera-Fernandez, A Bellelli… - Acta biomaterialia, 2017 - Elsevier
Naturally occurring antimicrobial peptides (AMPs) hold promise as future therapeutics
against multidrug resistant microorganisms. Recently, we have discovered that a derivative …

Potential of Exopolysaccharide from Porphyridium marinum to Contend with Bacterial Proliferation, Biofilm Formation, and Breast Cancer

N Gargouch, F Elleuch, I Karkouch, O Tabbene… - Marine drugs, 2021 - mdpi.com
Exopolysaccharide (EPS) from marine microalgae are promising sources of a new
generation of drugs. However, lot of them remain to be discovered and tested. In this study …

Antifungal mechanism of the combination of Cinnamomum verum and Pelargonium graveolens essential oils with fluconazole against pathogenic Candida strains

R Essid, M Hammami, D Gharbi, I Karkouch… - Applied Microbiology …, 2017 - Springer
The present study aimed to investigate the anti-Candida activity of ten essential oils (EOs)
and to evaluate their potential synergism with conventional drugs. The effect on secreted …

d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

A Di Grazia, F Cappiello, H Cohen, B Casciaro, V Luca… - Amino acids, 2015 - Springer
Naturally occurring antimicrobial peptides (AMPs) represent promising future antibiotics. We
have previously isolated esculentin-1a (1-21) NH 2, a short peptide derived from the frog …

The Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent …

A Di Grazia, F Cappiello, A Imanishi… - PloS one, 2015 - journals.plos.org
One of the many functions of skin is to protect the organism against a wide range of
pathogens. Antimicrobial peptides (AMPs) produced by the skin epithelium provide an …

Short symmetric-end antimicrobial peptides centered on β-turn amino acids unit improve selectivity and stability

N Dong, S Chou, J Li, C Xue, X Li, B Cheng… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are excellent candidates to combat the increasing number of
multi-or pan-resistant pathogens worldwide based on their mechanism of action, which is …

Alpha‐melanocyte stimulating hormone: an emerging anti‐inflammatory antimicrobial peptide

M Singh, K Mukhopadhyay - BioMed research international, 2014 - Wiley Online Library
The alpha‐melanocyte stimulating hormone (α‐MSH) is a neuropeptide belonging to the
melanocortin family. It is well known for its anti‐inflammatory and antipyretic effects and …

Alternating Cationic‐Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

N Frederiksen, PR Hansen, D Zabicka… - …, 2020 - Wiley Online Library
The influence of hydrophobicity on antibacterial activity versus the effect on the viability of
mammalian cells for peptide/peptoid hybrids was examined for oligomers based on the …