Oxysterol-binding protein-like 7 deficiency leads to ER stress-mediated apoptosis in podocytes and proteinuria

J Duara, M Torres, M Gurumani… - American Journal …, 2024 - journals.physiology.org
Chronic kidney disease (CKD) is associated with renal lipid dysmetabolism among a variety
of other pathways. We recently demonstrated that oxysterol-binding protein-like 7 (OSBPL7) …

TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin

J Wu, L Jiang, S Wang, L Peng, R Zhang… - International …, 2024 - Elsevier
The involvement of Interferon-stimulated exonuclease gene 20 (ISG20) has been reported in
renal clear cell carcinoma, hepatocellular carcinoma, and cervical cancer. However, its role …

RNA 8-羟基鸟嘌呤修饰: 旧貌新颜.

李虎杰, 曹正岳, 郑晓飞 - Chinese Journal of Biochemistry & …, 2024 - search.ebscohost.com
摘要细胞内存在多种类型的RNA 分子, 在调控细胞进程中各自发挥着重要的作用. RNA
修饰是在RNA 分子上添加化学基团, 修饰基团可以改变RNA 稳定性, 结构和功能, RNA …

A potential novel therapy addressing RNA oxidative damage in AKI

C Wan, C Zhang - Molecular Therapy, 2023 - cell.com
Oxidative stress plays a vital role in the pathogenesis of various diseases, as excessive free
radicals can damage cellular components including nucleic acid, lipid, and protein, resulting …