The transporter associated with antigen processing (TAP) is essential for peptide delivery
from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are …

Bovine respiratory tract disease is a multi-factorial disease complex involving several
viruses and bacteria. Viruses that play prominent roles in causing the bovine respiratory …

Detection and elimination of virus-infected cells by cytotoxic T lymphocytes depends on
recognition of virus-derived peptides presented by MHC class I molecules. A critical step in …

The transporter associated with antigen processing (TAP) is a key player in the major
histocompatibility class I-restricted antigen presentation and an attractive target for immune …

Bovine respiratory disease complex (BRDC) is an important cause of mortality and morbidity
in cattle; costing the dairy and beef industries millions of dollars annually, despite the use of …

Bovine respiratory disease complex (BRDC) is a multifactorial disease of cattle which
presents as bacterial and viral pneumonia. The causative agents of BRDC work in synergy …

Viruses that establish long‐term infections in their hosts have evolved a number of methods
to interfere with the activities of the innate and adaptive immune systems. Control of viral …

TAP1-TAP2 heterodimeric complexes are recognized as the transporter associated with
antigen processing of major histocompatibility complex class I peptides for recognition by …

Cytotoxic T-lymphocytes play an important role in the protection against viral infections,
which they detect through the recognition of virus-derived peptides, presented in the context …

CD8+ cytotoxic T lymphocytes (CTLs) play a critical role in the defense against viral
infections. In general, CD8+ CTLs recognize antigenic peptides in the context of the major …