Recent advances of chitosan formulations in biomedical applications

MAS Abourehab, S Pramanik, MA Abdelgawad… - International journal of …, 2022 - mdpi.com
Chitosan, a naturally abundant cationic polymer, is chemically composed of cellulose-based
biopolymers derived by deacetylating chitin. It offers several attractive characteristics such …

[HTML][HTML] Core-shell inorganic NPs@ MOF nanostructures for targeted drug delivery and multimodal imaging-guided combination tumor treatment

S Khan, M Falahati, WC Cho, Y Vahdani… - Advances in Colloid and …, 2023 - Elsevier
It is well known that metal-organic-framework (MOF) nanostructures have unique
characteristics such as high porosity, large surface areas, and adjustable biofunctionalities …

Chitosan-based intelligent polymeric networks for site-specific colon medication delivery: A comprehensive study on controlled release of diloxanide furoate and …

A Mahmood, A Mahmood, RM Sarfraz… - International Journal of …, 2024 - Elsevier
Oral medications are prone to gastric degradation and enzymatic inactivation, diminishing
their efficacy. This study investigates a solution by developing intelligent polymeric networks …

Folic acid-decorated alginate nanoparticles loaded hydrogel for the oral delivery of diferourylmethane in colorectal cancer

M Abbasi, M Sohail, MU Minhas, A Mahmood… - International Journal of …, 2023 - Elsevier
The disease-related suffering in colorectal cancer remains prevalent despite advancements
in the field of drug delivery. Chemotherapy-related side effects and non-specificity remain a …

[HTML][HTML] A novel pH-responsive hydrogel system based on Prunus armeniaca gum and acrylic acid: Preparation and evaluation as a potential candidate for controlled …

S Noureen, S Noreen, SA Ghumman… - European Journal of …, 2023 - Elsevier
Abstract pH-responsive hydrogels have become effective and attractive materials for the
controlled release of drugs at pre-determined destinations. In the present study, a novel …

Dynamic double cross-linked self-healing polysaccharide hydrogel wound dressing based on schiff base and thiol-alkynone reactions

Z Zhang, J Bu, B Li, H Xuan, Y Jin, H Yuan - International Journal of …, 2022 - mdpi.com
In this study, a hydrogel composite wound dressing with antibacterial and self-healing ability
was prepared using cysteine-modified carboxymethyl chitosan, sodium oxidized alginate …

Hydrogel-based intelligent delivery system for controlled release of diloxanide furoate

A Mahmood, A Mahmood, RM Sarfraz, H Ijaz, N Zafar… - Polymer Bulletin, 2023 - Springer
In current research work, pH responsive pectin-co-poly (MAA) hydrogels containing
diloxanide furoate were developed by graft polymerization of pectin and methacrylic acid, for …

[HTML][HTML] A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria

A Alshweiat, RO Al-Khresieh, KZ Alzarieni… - Saudi Pharmaceutical …, 2024 - Elsevier
Chitosan is known to exert antimicrobial activity without the need for any chemical
modification; however, new derivatives of chitosan can be created to target multi-drug …

Preparation, In Vitro Characterization, and Evaluation of Polymeric pH-Responsive Hydrogels for Controlled Drug Release

T Mahmood, RM Sarfraz, A Mahmood… - ACS …, 2024 - ACS Publications
The purpose of the current research is to formulate a smart drug delivery system for solubility
enhancement and sustained release of hydrophobic drugs. Drug solubility-related …

[HTML][HTML] Novel Natrosol/Pectin-co-poly (acrylate) based pH-responsive polymeric carrier system for controlled delivery of Tapentadol Hydrochloride

N Zafar, A Mahmood, S Ilyas, H Ijaz, RM Sarfraz… - Saudi Pharmaceutical …, 2023 - Elsevier
Abstract Background & Objectives This study aimed to create a controlled delivery system for
Tapentadol Hydrochloride by developing interpenetrating networks (IPNs) of Natrosol-Pectin …